Evidence map›Paper›PMID 22984007›Full record

Trial reportStroke2012

CT interpretation in a telestroke network: agreement among a spoke radiologist, hub vascular neurologist, and hub neuroradiologist.

Bart M Demaerschalk, Bentley J Bobrow, Rema Raman, Karin Ernstrom, Joseph M Hoxworth, Ameet C Patel, Terri-Ellen J Kiernan, Maria I Aguilar, Timothy J Ingall, David W Dodick and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Stroke, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00623350 (Stroke Team Remote Evaluation Using a Digital Observation Camera Arizona - The Initial Mayo Clinic Experience), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00623350 nacompletednot on this map

Stroke Team Remote Evaluation Using a Digital Observation Camera Arizona - The Initial Mayo Clinic Experience

TypeinterventionalSponsorMayo ClinicRan2007 to 2009Enrolled60ConditionsStroke, AcuteArmsTelephone, Two way audio/video telemedicine consult
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Telemedicine in Neurological Disorders: Opportunities and Challenges.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2019
    Review
  9. Review
  10. Interpretation of Brain CT Scans in the Field by Critical Care Physicians in a Mobile Stroke Unit.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018
    Article
  11. Telestroke.Current cardiology reports · 2017
    Review
  12. Review
  13. A comparison of direct and two-stage transportation of patients to hospital in Poland.International journal of environmental research and public health · 2015
    Article
  14. Imaging of prehospital stroke therapeutics.Expert review of cardiovascular therapy · 2015
    Review
  15. Pooled assessment of computed tomography interpretation by vascular neurologists in the STRokE DOC telestroke network.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2014
    Article
  16. Review
  17. The history and future of telestroke.Nature reviews. Neurology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bart M DemaerschalkDepartment of Neurology, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA. demaerschalk.bart@mayo.edu
Bentley J Bobrow
Rema Raman
Karin Ernstrom
Joseph M Hoxworth
Ameet C Patel
Terri-Ellen J Kiernan
Maria I Aguilar
Timothy J Ingall
David W Dodick
Brett C Meyer
Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) in Arizona—The Initial Mayo Clinic Experience (AZ TIME) Investigators

Funding

UltrasoundP50NS044148 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MEYER, BRETT C · 2003 to 2012
$15.1M
NINDS NIH HHS P50 NS044148
6 · The paper itself

Abstract

background and purposeThe American Stroke Association guidelines emphasized the need for further high-quality studies that assess agreement by radiologists and nonradiologists engaged in emergency telestroke assessments and decision-making. Therefore, the objective of this study was to determine the level of agreement of baseline brain CT scan interpretations of patients with acute stroke presenting to telestroke spoke hospitals between central reading committee neuroradiologists and each of 2 groups, spoke hospital radiologists and hub hospital vascular neurologists (telestrokologists).

methodsThe Stroke Team Remote Evaluation Using a Digital Observation Camera Arizona trial was a prospective, urban single-hub, rural 2-spoke, randomized, blinded, controlled trial of a 2-way, site-independent, audiovisual telemedicine and teleradiology system designed for remote evaluation of adult patients with acute stroke versus telephone consultation to assess eligibility for treatment with intravenous thrombolysis. In the telemedicine arm, the subjects' CT scans were interpreted by the hub telestrokologist and in the telephone arm by the spoke radiologist. All subjects' CT scans were subsequently interpreted centrally, independently, and blindly by 2 hub neuroradiologists. The primary CT outcome was determination of a CT-based contraindication to thrombolytic treatment. Kappa statistics and exact agreement rates were used to analyze interobserver agreement.

resultsFifty-four subjects underwent random assignment. The overall agreement for the presence of radiological contraindications to thrombolysis was excellent (0.91) and did not differ substantially between the hub telestrokologist to neuroradiologist and spoke radiologist to neuroradiologist (0.92 and 0.89, respectively).

conclusionsIn the context of a telestroke network designed to assess patients with acute stroke syndromes, agreement over the presence or absence of radiological contraindications to thrombolysis was excellent whether the comparisons were between a telestrokologist and neuroradiologist or between spoke radiologist and neuroradiologist. CLINICAL

trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT00623350.

Indexed as

BrainCardiologyFibrinolytic AgentsHumansNeurologyObserver VariationRadiologyStrokeTeleradiologyThrombolytic TherapyTomography, X-Ray ComputedFibrinolytic Agents

Identifiers

PMID22984007
PMCPMC3502613

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.