ArticleAdvances in nutrition (Bethesda, Md.)2012
Exploring the factors that affect blood cholesterol and heart disease risk: is dietary cholesterol as bad for you as history leads us to believe?
Article in Advances in nutrition (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Egg consumption and risk of coronary heart disease and stroke: dose-response meta-analysis of prospective cohort studies.BMJ (Clinical research ed.) · 2013Pooled it
- Consumption of Eggs Alone or Enriched with Annatto (Nutrients · 2023Trial
- Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.The American journal of clinical nutrition · 2020Trial
- Water content and cholesterol dynamics in various chicken meat cuts influenced by thermal processing methods: A multi-city assessment.Journal of advanced veterinary and animal research · 2026Article
- Emerging Biomarkers and Determinants of Lipoprotein Profiles to Predict CVD Risk: Implications for Precision Nutrition.Nutrients · 2024Review
- Influence of dietary cholesterol on metabolic syndrome risk in middle-aged Korean adults: using the Korean Genome and Epidemiology Study (KoGES).Lipids in health and disease · 2024Article
- Bidirectional causality between the levels of blood lipids and endometriosis: a two-sample mendelian randomization study.BMC women's health · 2024Article
- Egg Intake Is Associated with Lower Risks of Impaired Fasting Glucose and High Blood Pressure in Framingham Offspring Study Adults.Nutrients · 2023Article
- Protective cardiovascular benefits of exercise training as measured by circulating endothelial cells and high-density lipoprotein in adults.Journal of Taibah University Medical Sciences · 2022Article
- Machine Learning Methods for Hypercholesterolemia Long-Term Risk Prediction.Sensors (Basel, Switzerland) · 2022Article
- Phytonutrients of Bitter Apricot Seeds Modulate Human Lipid Profile and LDL Subfractions in Adults with Elevated Cholesterol Levels.International journal of environmental research and public health · 2022Article
- Cardiac biomarkers and detection methods for myocardial infarction.Molecular & cellular toxicology · 2022Review
- Association of eggs with dietary nutrient adequacy and cardiovascular risk factors in US adults.Public health nutrition · 2019Article
- Frequency and Quantity of Egg Intake Is Not Associated with Dyslipidemia: The Hellenic National Nutrition and Health Survey (HNNHS).Nutrients · 2019Article
- The application of six dietary scores to a Middle Eastern population: a comparative analysis of mortality in a prospective study.European journal of epidemiology · 2019Article
- Egg Intake Has No Adverse Association With Blood Lipids Or Glucose In Adolescent Girls.Journal of the American College of Nutrition · 2019Article
- Perspective: Limiting Dependence on Nonrandomized Studies and Improving Randomized Trials in Human Nutrition Research: Why and How.Advances in nutrition (Bethesda, Md.) · 2018Article
- 7-Dehydrocholesterol (7-DHC), But Not Cholesterol, Causes Suppression of Canonical TGF-β Signaling and Is Likely Involved in the Development of Atherosclerotic Cardiovascular Disease (ASCVD).Journal of cellular biochemistry · 2017Article
- A Snack Dietary Pattern Increases the Risk of Hypercholesterolemia in Northern Chinese Adults: A Prospective Cohort Study.PloS one · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper summarizes presentations given at the 2011 Experimental Biology meetings about the latest research and a paleoanthropological perspective pertaining to the relationship between dietary cholesterol intake and cardiovascular disease risk. For much of the past 50 years, a great deal of the scientific literature regarding dietary fat and cholesterol intake has indicated a strong positive correlation with heart disease. In recent years, however, there have been a number of epidemiological studies that did not support a relationship between cholesterol intake and cardiovascular disease. Further, a number of recent clinical trials that looked at the effects of long-term egg consumption (as a vehicle for dietary cholesterol) reported no negative impact on various indices of cardiovascular health and disease. Coupled with data indicating that the impact of lowering dietary cholesterol intake on serum LDL levels is small compared with other dietary and lifestyle factors, there is a need to consider how otherwise healthy foods can be incorporated in the diet to meet current dietary cholesterol recommendations. Because eggs are a healthful food, it is particularly important that sensible strategies be recommended for inclusions of eggs in a healthy diet.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.