Trial reportEndocrine2013
Racial differences in adiponectin and leptin in healthy premenopausal women.
Trial report in Endocrine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 37 citations in OpenAlex.
- Racial Differences in Relative Skeletal Muscle Mass Loss During Diet-Induced Weight Loss in Women.Obesity (Silver Spring, Md.) · 2018Trial
- Leptin resistance in children with in utero exposure to maternal obesity and gestational diabetes.Pediatric obesity · 2023Article
- Obesity Pillars Roundtable: Body mass index and body composition in Black and Female individuals. Race-relevant or racist? Sex-relevant or sexist?Obesity pillars · 2022Article
- Adiponectin: friend or foe in obesity and inflammation.Medical review (2021) · 2022Review
- Race-specific associations of urinary phenols and parabens with adipokines in midlife women: The Study of Women's Health Across the Nation (SWAN).Environmental pollution (Barking, Essex : 1987) · 2022Article
- Sex and Body Circumferences Associated with Serum Leptin in African American Adults.Journal of women's health (2002) · 2021Article
- Sex differences on adipose tissue remodeling: from molecular mechanisms to therapeutic interventions.Journal of molecular medicine (Berlin, Germany) · 2020Review
- The Potential for Plant-Based Diets to Promote Health Among Blacks Living in the United States.Nutrients · 2019Review
- A novel biomarker of cardiometabolic pathology in schizophrenia?Journal of psychiatric research · 2019Article
- Racial Differences in Cardiovascular Biomarkers in the General Population.Journal of the American Heart Association · 2019Article
- Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.American journal of human genetics · 2019Article
- Food and financial coping strategies during the monthly Supplemental Nutrition Assistance Program cycle.SSM - population health · 2019Article
- Pro-inflammatory cytokines and growth factors in human milk: an exploratory analysis of racial differences to inform breast cancer etiology.Breast cancer research and treatment · 2018Article
- Adiponectin, in contrast to leptin, is not associated with body mass index, waist circumference and HOMA-IR in subjects of a west-African population.Physiological reports · 2018Article
- Endometrial cancer associated biomarkers in bariatric surgery candidates: exploration of racial differences.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017Observational
- Systemic FDiversity and equality in health and care · 2017Article
- Relationship of adiponectin and leptin with autoimmunity in children with new-onset type 1 diabetes: a pilot study.Pediatric diabetes · 2016Article
- Obesity adversely affects serum anti-müllerian hormone (AMH) levels in Caucasian women.Journal of assisted reproduction and genetics · 2015Article
- Racial/Ethnic Differences in Insulin Resistance and Beta Cell Function: Relationship to Racial Disparities in Type 2 Diabetes among African Americans versus Caucasians.Current obesity reports · 2015Review
- The Interplay Between Sex, Ethnicity, and Adipose Tissue Characteristics.Current obesity reports · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The aim of this article is to longitudinally investigate racial differences in serum adiponectin and leptin in European-American (EA) and African-American (AA) women in the overweight and weight-reduced states. Sixty-two EA and 58 AA premenopausal women were weight reduced from body mass index (BMI) 27-30 kg/m(2) to BMI ≤ 24. Fasting serum adiponectin and leptin were determined; body composition and intra-abdominal adipose tissue (IAAT) were measured with dual-energy X-ray absorptiometry and computed tomography, respectively. In repeated-measure MANOVA, there was a significant race effect for IAAT and total fat mass; compared to AA women, EA women had higher IAAT and total fat mass (p < 0.0001 and p = 0.027, respectively). In the mixed-model for adiponectin that adjusted for IAAT, limb fat, and total fat, race was significantly associated with adiponectin (p = 0.046). AA women had significantly lower adjusted adiponectin compared to EA women at baseline [7.67 (6.85, 8.60) vs. 9.32 (8.34, 10.4) μg/ml, p < 0.05] and following weight loss [9.75 (8.70, 10.9) vs. 11.8 (10.6, 13.2) μg/ml, p < 0.05]. In a mixed-model for leptin that adjusted for insulin, estradiol, and fat mass, race was significantly associated with leptin (p < 0.0001). AA women had significantly higher adjusted leptin compared to EA women at baseline [24.7 (22.3, 27.4) vs. 19.9 (18.1, 21.8) ng/dl, p < 0.05] and following weight loss [11.7 (10.2, 13.3) vs. 8.48 (7.50, 9.57) ng/dl, p < 0.05]. Despite having a more favorable body fat distribution, AA women had lower adjusted adiponectin and higher leptin. Differences in body composition and fat distribution do not appear to be significant factors in explaining lower adiponectin and higher leptin in AA women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.