Evidence map›Paper›PMID 22983383›Full record

ReviewCellular and molecular life sciences : CMLS2013

Control by a hair's breadth: the role of microRNAs in the skin.

Matthew S Ning, Thomas Andl

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 49 citations in OpenAlex.

  1. Emerging role of ferroptosis in ultraviolet radiation-driven skin photoaging: a narrative review.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Targeting microRNA for improved skin health.Health science reports · 2021
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. The Role of microRNAs in Organismal and Skin Aging.International journal of molecular sciences · 2020
    Review
  12. Burns in the Elderly: Potential Role of Stem Cells.International journal of molecular sciences · 2020
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew S NingDepartment of Medicine/Division of Dermatology, Vanderbilt University Medical Center, Medical Center North, Room A2310B, 1161 21st Avenue South, Nashville, TN 37232-2600, USA.
Thomas Andl
Vanderbilt University Medical Center · US

Funding

The role of microRNA miR-31 in skin biologyR01AR061474 · NIAMS · VANDERBILT UNIVERSITY · PI ANDL, THOMAS · 2011 to 2015
$1.7M
NIAMS NIH HHS 1R01AR061474-01NIAMS NIH HHS R01 AR061474
6 · The paper itself

Abstract

MicroRNAs have continued to attract enormous interest in the scientific community ever since their discovery. Their allure stems from their unique role in posttranscriptional gene expression control as well as their potential application as therapeutic targets in various disease pathologies. While much is known concerning their general biological function, such as their interaction with RNA-induced silencing complexes, many important questions still remain unanswered, especially regarding their functions in the skin. In this review, we summarize our current knowledge of the role of microRNAs in the skin in order to shine new light on our understanding of cutaneous biology and emphasize the significance of these small, single-stranded RNA molecules in the largest organ of the human body. Key events in epidermal and hair follicle biology, including differentiation, proliferation, and pigmentation, all involve microRNAs. We explore the role of microRNAs in several cutaneous processes, such as appendage formation, wound-healing, epithelial-mesenchymal transition, carcinogenesis, immune response, and aging. In addition, we discuss current trends in research and offer suggestions for future studies.

Indexed as

AnimalsCultureEpithelial-Mesenchymal TransitionHairHair FollicleHumansMicroRNAsModels, BiologicalPhylogenyScienceSkinSkin Physiological PhenomenaMicroRNAs

Identifiers

PMID22983383
PMCPMC3548021
OpenAlexW2064600799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.