Evidence map›Paper›PMID 22983222›Full record

ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2013

Prognostic biological features in neck dissection specimens.

Julia A Woolgar, Asterios Triantafyllou, James S Lewis, Jennifer Hunt, Michelle D Williams, Robert P Takes, Lester D R Thompson, Pieter J Slootweg, Kenneth O Devaney, Alfio Ferlito

Abstract readReview
PubMed Publisher
In one paragraph

Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Frequency, predictors, and prognostic impact of intraparotid lymph node recurrence in oral cavity squamous cell carcinoma: a retrospective case-control study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  4. Review
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  9. Article
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  14. Prevalence of Skip Metastases to Cervical Lymph-Nodes in Oral cavity Cancer in Eastern India-an observational study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
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  18. Review
  19. Review
  20. Clinical analysis of neck node metastasis in oral cavity cancer.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 4 countries.

Julia A WoolgarOral Pathology, School of Dentistry and Dental Hospital, University of Liverpool, Liverpool, UK.
Asterios Triantafyllou
James S Lewis
Jennifer Hunt
Michelle D Williams
Robert P Takes
Lester D R Thompson
Pieter J Slootweg
Kenneth O Devaney
Alfio Ferlito
University of Liverpool · GBHenry Ford Allegiance Health · USRadboud University Medical Center · NLRadboud University Nijmegen · NLThe University of Texas MD Anderson Cancer Center · USUniversity of Arkansas for Medical Sciences · USUniversity of Udine · ITWashington University in St. Louis · USWoodland Hills Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The superior prognostic value offered by routine histopathological staging of neck dissections, as compared to clinical staging using palpation and modern imaging techniques, is well established in the literature concerning the management of squamous cell carcinoma of the head and neck. In this review, we discuss the definitions and criteria used in standardised routine histopathological reporting and explore additional potential nodal prognostic features. In addition, we critically appraise the value of immunohistochemistry, histochemistry, molecular and other non-morphological techniques and suggest tumour and host features that merit further investigations.

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsHumansLymphatic MetastasisLymph NodesNeck DissectionPrognosisSquamous Cell Carcinoma of Head and Neck

Identifiers

PMID22983222
OpenAlexW2040469088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.