Evidence map›Paper›PMID 22982528›Full record

ArticleGenomics2013

Identifying human-rhesus macaque gene orthologs using heterospecific SNP probes.

Sree Kanthaswamy, Jillian Ng, Cody T Ross, Jessica Satkoski Trask, David Glenn Smith, Vince S Buffalo, Joseph N Fass, Dawei Lin

Open access · greenAbstract read
In one paragraph

Article in Genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Comparative medicine · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sree KanthaswamyMolecular Anthropology Lab., Dept. of Anthropology, UC Davis, CA, USA. skanthaswamy@ucdavis.edu
Jillian Ng
Cody T Ross
Jessica Satkoski Trask
David Glenn Smith
Vince S Buffalo
Joseph N Fass
Dawei Lin
Museum of Indian Arts and Culture · USUniversity of California, Davis · US

Funding

ZONA PELLUCIDA PEPTIDES AS IMMUNOCONTRACEPTIVE ANTIGENSP51RR000169 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI HYDE, DALLAS MELVIN · 1985 to 2011
$126.2M
Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura Marcu · 2002 to 2026
$84.9M
GENETICALLY DEFINED HERPES/RETROVIRUS SPF MACAQUES: AIDS: VACCINE DVMTU24RR018144 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI LERCHE, NICHOLAS WILLIAM · 2002 to 2011
$15.7M
GENETIC MANAGEMENT OF MECAQUES BY DNA RFLP ANALYSISR24RR005090 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI SMITH, DAVID GLENN · 1988 to 2011
$3.7M
Development, Management and Use of a SNP Map for Rhesus MacaqueR24RR025871 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SMITH, DAVID GLENN · 2009 to 2011
$1.6M
Intramural NIH HHSNCI NIH HHS P30 CA093373NCRR NIH HHS P51 RR000169NCRR NIH HHS R24 RR005090NCRR NIH HHS R24 RR025871NCRR NIH HHS RR000169-48NCRR NIH HHS RR005090NCRR NIH HHS RR018144-07NCRR NIH HHS RR025871NCRR NIH HHS U24 RR018144
6 · The paper itself

Abstract

We genotyped a Chinese and an Indian-origin rhesus macaque using the Affymetrix Genome-Wide Human SNP Array 6.0 and cataloged 85,473 uniquely mapping heterospecific SNPs. These SNPs were assigned to rhesus chromosomes according to their probe sequence alignments as displayed in the human and rhesus reference sequences. The conserved gene order (synteny) revealed by heterospecific SNP maps is in concordance with that of the published human and rhesus macaque genomes. Using these SNPs' original human rs numbers, we identified 12,328 genes annotated in humans that are associated with these SNPs, 3674 of which were found in at least one of the two rhesus macaques studied. Due to their density, the heterospecific SNPs allow fine-grained comparisons, including approximate boundaries of intra- and extra-chromosomal rearrangements involving gene orthologs, which can be used to distinguish rhesus macaque chromosomes from human chromosomes.

Indexed as

GenesPolymorphism, Single NucleotideAnimalsBase SequenceChromosome MappingDNADNA ProbesGenome, HumanHumansMacacaSequence AlignmentSyntenyDNADNA Probes

Identifiers

PMID22982528
PMCPMC3534948
OpenAlexW1997962566

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.