Evidence map›Paper›PMID 22982425›Full record

Trial reportThe Journal of urology2013

The effect of urodynamic testing on clinical diagnosis, treatment plan and outcomes in women undergoing stress urinary incontinence surgery.

Larry T Sirls, Holly E Richter, Heather J Litman, Kimberly Kenton, Gary E Lemack, Emily S Lukacz, Stephen R Kraus, Howard B Goldman, Alison Weidner, Leslie Rickey and 4 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The Journal of urology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Detrusor Overactivity and Urodynamics.Neurourology and urodynamics · 2026
    Review
  7. Article
  8. 2024 Canadian Urological Association guideline: Female stress urinary incontinence.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Evaluating progress on longstanding issues.Nature reviews. Urology · 2014
    Article
  17. Article
  18. [Stress incontinence in elderly women].Der Urologe. Ausg. A · 2013
    Article
  19. Article
  20. Are urodynamics still useful?Canadian Urological Association journal = Journal de l'Association des urologues du Canada
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 1 country.

Larry T SirlsDepartment Urology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA. lsirls@mac.com
Holly E Richter
Heather J Litman
Kimberly Kenton
Gary E Lemack
Emily S Lukacz
Stephen R Kraus
Howard B Goldman
Alison Weidner
Leslie Rickey
Peggy Norton
Halina M Zyczynski
John W Kusek
Urinary Incontinence Treatment Network
Beaumont Hospital, Royal Oak · USCleveland Clinic · USDuke University · USLoyola University Chicago · USMagee-Womens Hospital · USNational Institutes of Health · USNew England Research Institutes · USThe University of Texas at San Antonio · USThe University of Texas Southwestern Medical Center · USUniversity of Alabama at Birmingham · USUniversity of California, San Diego · USUniversity of Maryland, Baltimore · USUniversity of Utah · US

Funding

Urinary Incontinence Treatment Network: DCCU01DK058229 · NIDDK · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI TENNSTEDT, SHARON L · 2000 to 2012
$16.1M
UAB Continence Treatment Center U01DK060380 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RICHTER, HOLLY E · 2001 to 2009
$3.9M
Urinary Incontinence Treatment NetworkU01DK058225 · NIDDK · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ZYCZYNSKI, HALINA M · 2000 to 2009
$3.8M
UCSD INCONTINENCE TREATMENT CENTERU01DK060401 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALBO, MICHAEL · 2001 to 2010
$3.6M
Continuation of the Urinary Incontinence Treatment Network (UITN)U01DK060379 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA · 2001 to 2009
$3.6M
UTAH URINARY INCONTINENCE TREATMENT NETWORK (UUITN)U01DK060393 · NIDDK · UNIVERSITY OF UTAH · PI NORTON, PEGGY A · 2001 to 2009
$3.4M
Urinary Incontinence Treatment NetworkU01DK058231 · NIDDK · WILLIAM BEAUMONT HOSPITAL RESEARCH INST · PI SIRLS, LARRY T · 2000 to 2009
$3.3M
Urinary Incontinence Treatment Network (UITN)U01DK060397 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI CHAI, TOBY C · 2001 to 2010
$2.7M
Urinary Incontinence Treatment NetworkU01DK060395 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI ZIMMERN, PHILIPPE E · 2001 to 2009
$2.4M
The Urinary Incontinence Treatment NetworkU01DK058234 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KRAUS, STEPHEN R · 2000 to 2009
$2.3M
NIDDK NIH HHS U01 DK058225NIDDK NIH HHS U01 DK058229NIDDK NIH HHS U01 DK058231NIDDK NIH HHS U01 DK058234NIDDK NIH HHS U01 DK060379NIDDK NIH HHS U01 DK060380NIDDK NIH HHS U01 DK060393NIDDK NIH HHS U01 DK060395NIDDK NIH HHS U01 DK060397NIDDK NIH HHS U01 DK060401NIDDK NIH HHS U01 DK58225NIDDK NIH HHS U01DK58229NIDDK NIH HHS U01 DK58231NIDDK NIH HHS U01 DK58234NIDDK NIH HHS U01 DK60379NIDDK NIH HHS U01DK60380NIDDK NIH HHS U01 DK60393NIDDK NIH HHS U01 DK60395NIDDK NIH HHS U01 DK60397NIDDK NIH HHS U01DK60401
6 · The paper itself

Abstract

purposeWe evaluated the influence of preoperative urodynamic studies on diagnoses, global treatment plans and outcomes in women treated with surgery for uncomplicated stress predominant urinary incontinence. MATERIALS AND

methodsWe performed a secondary analysis from a multicenter, randomized trial of the value of preoperative urodynamic studies. Physicians provided diagnoses before and after urodynamic studies and global treatment plans, defined as proceeding with surgery, surgery type, surgical modification and nonoperative therapy. Treatment plan changes and surgical outcomes between office evaluation and office evaluation plus urodynamic studies were compared by the McNemar test.

resultsOf 315 subjects randomized to urodynamic studies after office evaluation 294 had evaluable data. Urodynamic studies changed the office evaluation diagnoses in 167 women (56.8%), decreasing the diagnoses of overactive bladder-wet (41.6% to 25.2%, p <0.001), overactive bladder-dry (31.4% to 20.8%, p = 0.002) and intrinsic sphincter deficiency (19.4% to 12.6%, p = 0.003) but increasing the diagnosis of voiding dysfunction (2.2% to 11.9%, p <0.001). After urodynamic studies physicians canceled surgery in 4 of 294 women (1.4%), changed the incontinence procedure in 13 (4.4%) and planned to modify mid urethral sling tension (more or less obstructive) in 20 women (6.8%). Nonoperative treatment plans changed in 40 of 294 women (14%). Urodynamic study driven treatment plan changes were not associated with treatment success (OR 0.96, 95% CI 0.41, 2.25, p = 0.92) but they were associated with increased postoperative treatment for urge urinary incontinence (OR 3.23, 95% CI 1.46, 7.14, p = 0.004).

conclusionsUrodynamic studies significantly changed clinical diagnoses but infrequently changed the global treatment plan or influenced surgeon decision to cancel, change or modify surgical plans. Global treatment plan changes were associated with increased treatment for postoperative urgency urinary incontinence.

Indexed as

UrodynamicsFemaleHumansTreatment OutcomeUrinary Incontinence, Stress

Identifiers

PMID22982425
PMCPMC4363108
OpenAlexW2103519754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.