Evidence map›Paper›PMID 22982285›Full record

ArticleInfant behavior & development2012

Relation between early motor delay and later communication delay in infants at risk for autism.

A N Bhat, J C Galloway, R J Landa

Open access · greenAbstract read
In one paragraph

Article in Infant behavior & development, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 4 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 4 syntheses or guidelines pooled it, 322 citations in OpenAlex.

  1. Pooled it
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  15. An Acoustic Analysis of Speech Motor Performance in Autistic Children.Journal of speech, language, and hearing research : JSLHR · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Atypical Postural Control Variability and Coordination Persist Into Middle and Older Adulthood in Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  20. Observational

76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

A N BhatPhysical Therapy Program, Department of Kinesiology, University of Connecticut, United States.
J C Galloway
R J Landa
Kennedy Krieger Institute · USUniversity of Connecticut · USUniversity of Delaware · US

Funding

Autism: Social And Communication Predictors in SiblingsR01MH059630 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI LANDA, REBECCA JEAN · 2001 to 2016
$10.7M
SENSORIMOTOR INTEGRATION IN CHILDREN WITH AUTISMU54MH066417 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI BLUE, MARY E · 2003 to 2007
$7.1M
NIMH NIH HHS 154MH066417NIMH NIH HHS MH59630NIMH NIH HHS R01 MH059630NIMH NIH HHS U54 MH066417
6 · The paper itself

Abstract

backgroundMotor delays have been reported in retrospective studies of young infants who later develop Autism Spectrum Disorders (ASDs).

objectiveIn this study, we prospectively compared the gross motor development of a cohort at risk for ASDs; infant siblings of children with ASDs (AU sibs) to low risk typically developing (LR) infants.

methods24 AU sibs and 24 LR infants were observed at 3 and 6 months using a standardized motor measure, the Alberta Infant Motor Scale (AIMS). In addition, as part of a larger study, the AU sibs also received a follow-up assessment to determine motor and communication performance at 18 months using the Mullen Scales of Early Learning.

resultsSignificantly more AU sibs showed motor delays at 3 and 6 months than LR infants. The majority of the AU sibs showed both early motor delays and later communication delays. LIMITATIONS: Small sample size and limited follow-up.

conclusionsEarly motor delays are more common in AU sibs than LR infants. Communication delays later emerged in 67-73% of the AU sibs who had presented with early motor delays. Overall, early motor delays may be predictive of future communication delays in children at risk for autism.

Indexed as

CommunicationAutistic DisorderChild DevelopmentDevelopmental DisabilitiesFemaleHumansInfantLanguage Development DisordersLongitudinal StudiesMaleMotor SkillsRisk FactorsSiblingsSocial Behavior

Identifiers

PMID22982285
PMCPMC3538350
OpenAlexW1992791476

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.