Evidence map›Paper›PMID 22981716›Full record

ReviewBrain and language2013

Functional imaging of the thalamus in language.

Daniel A Llano

Abstract readReview
In one paragraph

Review in Brain and language, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Redefining bilingualism as a spectrum of experiences that differentially affects brain structure and function.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Trial
  3. Article
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  13. Review
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  17. Thalamic Aphasia: a Review.Current neurology and neuroscience reports · 2022
    Review
  18. Stroke disconnectome decodes reading networks.Brain structure & function · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Daniel A LlanoUniversity of Illinois at Urbana-Champaign, Department of Molecular and Integrative Physiology, USA. d-llano@illinois.edu

Funding

Age-Related changes in GABAergic influence on auditory corticothalamic projectionR03DC012125 · NIDCD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LLANO, DANIEL A · 2011 to 2013
$445k
NIDCD NIH HHS R03 DC012125
6 · The paper itself

Abstract

Herein, the literature regarding functional imaging of the thalamus during language tasks is reviewed. Fifty studies met criteria for analysis. Two of the most common task paradigms associated with thalamic activation were generative tasks (e.g. word or sentence generation) and naming, though activation was also seen in tasks that involve lexical decision, reading and working memory. Typically, thalamic activation was seen bilaterally, left greater than right, along with activation in frontal and temporal cortical regions. Thalamic activation was seen with perceptually challenging tasks, though few studies rigorously correlated thalamic activation with measures of attention or task difficulty. The peaks of activation loci were seen in virtually all thalamic regions, with a bias towards left-sided and midline activation. These analyses suggest that the thalamus may be involved in processes that involve manipulations of lexical information, but point to the need for more systematic study of the thalamus using language tasks.

Indexed as

Functional NeuroimagingHumansLanguageSpeechThalamus

Identifiers

PMID22981716
PMCPMC4836874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.