Evidence map›Paper›PMID 22981021›Full record

Trial reportJournal of affective disorders2013

Quality of life among patients with bipolar disorder in primary care versus community mental health settings.

Christopher J Miller, Kristen M Abraham, Laura A Bajor, Zongshan Lai, Hyungjin Myra Kim, Kristina M Nord, David E Goodrich, Mark S Bauer, Amy M Kilbourne

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of affective disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Self-efficacy and quality of life among people with bipolar disorder.The Journal of nervous and mental disease · 2014
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Bipolar Disorder and Population Health.Psychiatric services (Washington, D.C.) · 2017
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christopher J MillerCenter for Organization, Leadership, and Management Research, VA Boston Healthcare System, 150 S. Huntington Ave. 152M, Boston, MA 02130, United States. Christopher.Miller8@va.gov
Kristen M Abraham
Laura A Bajor
Zongshan Lai
Hyungjin Myra Kim
Kristina M Nord
David E Goodrich
Mark S Bauer
Amy M Kilbourne

Funding

Implementing Chronic Care Management for Bipolar DisorderR01MH079994 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KILBOURNE, AMY M · 2008 to 2012
$3.3M
NIMH NIH HHS R01 MH079994NIMH NIH HHS R01 MH79994
6 · The paper itself

Abstract

introductionBipolar disorder is associated with functional impairment across a number of domains, including health-related quality of life (HRQOL). Many patients are treated exclusively in primary care (PC) settings, yet little is known how HRQOL outcomes compare between PC and community mental health (CMH) settings. This study aimed to explore the correlates of HRQOL across treatment settings using baseline data from a multisite, randomized controlled trial for adults with bipolar disorder.

methodsHRQOL was measured using the SF-12 physical (PCS) and mental (MCS) composite scale scores. Independent sample t-tests were calculated to compare differences in HRQOL between settings. Multivariate regression models then examined the effect of treatment setting on HRQOL, adjusting for covariate demographic factors, mood symptoms (Internal State Scale), hazardous drinking (AUDIT-C), and substance abuse.

resultsA total of 384 enrolled participants completed baseline surveys. MCS and PCS scores reflected similar impairment in HRQOL across PC and CMH settings (p=0.98 and p=0.49, respectively). Depressive symptoms were associated with lower MCS scores (B=-0.68, p<0.001) while arthritis/chronic pain was strongly related to lower PCS scores (B=-5.23, p<0.001). LIMITATIONS: This study lacked a formal diagnostic interview, relied on cross-sectional self-report, and sampled from a small number of sites in two states. DISCUSSION: Participants reported similar impairments in both mental and physical HRQOL in PC and CMH treatment settings, emphasizing the need for integrated care for patients with bipolar disorder regardless of where they present for treatment.

Indexed as

Community Mental Health CentersPrimary Health CareQuality of LifeAdultArthritisBipolar DisorderChronic PainCross-Sectional StudiesDepressionFemaleHealth Services ResearchHealth SurveysHumansMaleMiddle AgedTreatment Outcome

Identifiers

PMID22981021
PMCPMC3554842

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.