Evidence map›Paper›PMID 22978910›Full record

ArticleThe Journal of the Acoustical Society of America2012

Cancellous bone fast and slow waves obtained with Bayesian probability theory correlate with porosity from computed tomography.

Joseph J Hoffman, Amber M Nelson, Mark R Holland, James G Miller

Abstract readComparative Study
In one paragraph

Article in The Journal of the Acoustical Society of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Ultrasonic Assessment of Cancellous Bone Based on the Two-Wave Phenomenon.Advances in experimental medicine and biology · 2022
    Article
  2. Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020
    Review
  3. Article
  4. Article
  5. Article
  6. Ultrasound to assess bone quality.Current osteoporosis reports · 2014
    Article
  7. Article
  8. Article
  9. New perspectives in echographic diagnosis of osteoporosis on hip and spine.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph J HoffmanDepartment of Physics, Washington University in St. Louis, St. Louis, Missouri 63139, USA.
Amber M Nelson
Mark R Holland
James G Miller

Funding

The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI SILVA, MATTHEW J · 2009 to 2018
$5.7M
Enhancing Bone Quality Assessment Using Quantitative UltrasoundR01AR057433 · NIAMS · WASHINGTON UNIVERSITY · PI MILLER, JAMES GEGAN · 2009 to 2012
$1.3M
IN VIVO MICROCT SYSTEMS10RR023660 · NCRR · WASHINGTON UNIVERSITY · PI SILVA, MATTHEW J. · 2007 to 2007
$317k
NCRR NIH HHS S10 RR023660NIAMS NIH HHS P30 AR057235NIAMS NIH HHS P30AR057235NIAMS NIH HHS R01 AR057433NIAMS NIH HHS R01AR057433
6 · The paper itself

Abstract

A Bayesian probability theory approach for separating overlapping ultrasonic fast and slow waves in cancellous bone has been previously introduced. The goals of this study were to investigate whether the fast and slow waves obtained from Bayesian separation of an apparently single mode signal individually correlate with porosity and to isolate the fast and slow waves from medial-lateral insonification of the calcaneus. The Bayesian technique was applied to trabecular bone data from eight human calcanei insonified in the medial-lateral direction. The phase velocity, slope of attenuation (nBUA), and amplitude were determined for both the fast and slow waves. The porosity was assessed by micro-computed tomography (microCT) and ranged from 78.7% to 94.1%. The method successfully separated the fast and slow waves from medial-lateral insonification of the calcaneus. The phase velocity for both the fast and slow wave modes showed an inverse correlation with porosity (R(2) = 0.73 and R(2) = 0.86, respectively). The slope of attenuation for both wave modes also had a negative correlation with porosity (fast wave: R(2) = 0.73, slow wave: R(2) = 0.53). The fast wave amplitude decreased with increasing porosity (R(2) = 0.66). Conversely, the slow wave amplitude modestly increased with increasing porosity (R(2) = 0.39).

Indexed as

Bayes TheoremImage Interpretation, Computer-AssistedX-Ray MicrotomographyBone and BonesHumansMarkov ChainsMonte Carlo MethodOsteoporosisPorosityRadiographic Image Interpretation, Computer-AssistedTime FactorsUltrasonography

Identifiers

PMID22978910
PMCPMC3460989

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.