Evidence map›Paper›PMID 22978535›Full record

Trial reportPediatrics international : official journal of the Japan Pediatric Society2013

Respiratory viruses in neonates hospitalized with acute lower respiratory tract infections.

Hye Jung Cho, So-Yeon Shim, Dong Woo Son, Yong Han Sun, Hann Tchah, In-Sang Jeon

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Pediatrics international : official journal of the Japan Pediatric Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Human metapneumovirus in patients hospitalized with acute respiratory infections: A meta-analysis.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Update on Human Rhinovirus and Coronavirus Infections.Seminars in respiratory and critical care medicine · 2016
    Review
  8. Article
  9. Article
  10. Rapid replacement of human respiratory syncytial virus A with the ON1 genotype having 72 nucleotide duplication in G gene.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hye Jung ChoDepartment of Pediatrics, Gachon University Gil Hospital, Incheon, Korea.
So-Yeon Shim
Dong Woo Son
Yong Han Sun
Hann Tchah
In-Sang Jeon
Gachon University Gil Hospital · KRGachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe burden of respiratory syncytial virus (RSV) in neonates has not been clearly studied. The aims of this study were to determine the overall distribution of respiratory viruses in neonates hospitalized with acute lower respiratory tract infectiosns (ALRI) and to describe the clinical characteristics of RSV infections in these neonates.

methodsFrom January 2009 through May 2010, neonates aged <1 month who were hospitalized with ALRI and did not have underlying disease were included in the study. Viruses were identified on multiplex reverse transcription polymerase chain reaction using nasal swab samples. Clinical variables were evaluated between the RSV and non-RSV infection groups.

resultsOf the 108 infants included in the study, 46 (42.6%) had RSV; human rhinovirus (18.5%), human parainfluenza virus 3 (7.5%), and human metapneumovirus (3.7%) were the next most common infections. Codetections accounted for 8.3% of the cases. Crowding increased the risk of RSV infection compared to the non-RSV group (OR, 16.5; P = 0.001). The RSV group had a greater incidence of dyspnea (P = 0.027), pneumonia (P < 0.001), requirement for oxygen (P < 0.001), and prolonged hospitalization (P = 0.011) than the non-RSV group.

conclusionsRSV was the most common viral etiology in neonates without underlying diseases who were hospitalized with ALRI. The disease severity of RSV infection was worse than that of other detected viral infections. Strict prevention strategies should be considered in overcrowded situations.

Indexed as

Bronchiolitis, ViralDNA, ViralFemaleHospitalizationHumansInfant, NewbornMalePneumonia, ViralProspective StudiesRepublic of KoreaRespiratory Syncytial Virus InfectionsReverse Transcriptase Polymerase Chain ReactionRisk FactorsSeverity of Illness IndexSingle-Blind MethodDNA, Viral

Identifiers

PMID22978535
PMCPMC7167731
OpenAlexW1913551191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.