Evidence map›Paper›PMID 22978371›Full record

ArticleBMC infectious diseases2012

Cerebral vasculitis associated with Schistosoma mansoni infection.

Guillaume Camuset, Valérie Wolff, Christian Marescaux, Ahmed Abou-Bacar, Ermanno Candolfi, Nicolas Lefebvre, Daniel Christmann, Yves Hansmann

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Post-infectious central nervous system vasculitides in adults: an underdiagnosed and treatable disease : Part I. Overview.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  2. Review
  3. Review
  4. Stroke in Patients with Schistosomiasis: Review of Cases in Literature.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Review
  5. Clinical Spectrum of Schistosomiasis: An Update.Journal of clinical medicine · 2021
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Guillaume CamusetUnité des Maladies Infectieuses, Centre Hospitalier Universitaire La Réunion, Site Sud, BP 350, 97448, Saint-Pierre, Ile de la Réunion, France. guillaume.camuset@chu-reunion.fr
Valérie Wolff
Christian Marescaux
Ahmed Abou-Bacar
Ermanno Candolfi
Nicolas Lefebvre
Daniel Christmann
Yves Hansmann
Hôpitaux Universitaires de Strasbourg · FRUniversité de Strasbourg · FRCentre Hospitalier Universitaire de La Réunion · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral involvement in schistosomiasis is not rare, but it is underdiagnosed because of the lack of clinical suspicion and the frequency of asymptomatic forms. Neurologic complications are generally supported by granuloma formation around ectopic eggs which have migrated to the brain. Moreover, vascular lesions and cerebral arteritis have been well documented in histopathological studies. Nevertheless, cerebral vasculitis in later stages of the Schistosoma mansoni infection have not yet been described in living subjects. CASE PRESENTATION: A 28-year-old french woman had a stroke linked with cerebral vasculitis, 6 monthes after returning from Burkina-Faso. At the same time, a S. mansoni disseminated infection was diagnosed. She suffered from a new stroke after undertaking praziquantel therapy, which lead us to associate the S. mansoni infection and cerebral vasculitis.

conclusionThis is the first report of such association, since cerebral vasculitis has never been described in later stages of the S. mansoni infection. Although the causal link between the two pathologies could not be proved, we suggest that S. mansoni is able to cause severe vascular damage in cerebral vessels. Schistosomiasis must be investigated in the event of a brain infarct in young people, particularly in patients originating or returning from an endemic area.

Indexed as

AdultAnimalsAnthelminticsBurkina FasoFemaleFranceHumansPraziquantelSchistosoma mansoniSchistosomiasis mansoniStrokeVasculitis, Central Nervous SystemAnthelminticsPraziquantel

Identifiers

PMID22978371
PMCPMC3482565
OpenAlexW2112068821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.