ArticleExperimental and therapeutic medicine2011
Antioxidant activity and antiapoptotic effect of Asparagus racemosus root extracts in human lung epithelial H460 cells.
Article in Experimental and therapeutic medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 27 citations in OpenAlex.
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Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study examined the antioxidant activity and protective effect of extracts from Asparagus racemosus roots against Lipofectamine-induced apoptosis. Five fractions from a successive extraction process ranging from non-polar to more polar solvents were obtained. The total saponin content as a marker in terms of diosgenin equivalent value of the root extracts was found to be in the range of 240-420 μg/mg extract, with higher values for the ethanol and aqueous fractions. The antioxidant activity measured using the DPPH method in terms of mean effective concentration (EC(50)) of the aqueous fraction was found to be 600 μg/ml as compared to 1.5 μg/ml of ascorbic acid. It is proposed that Asparagus racemosus root extracts effectively inhibit Lipofectamine-induced apoptosis by their protective effect, and may serve as an advantageous alternative option for gene delivery.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.