ArticleClinical epidemiology2012
Positive predictive values of the coding for bisphosphonate therapy among cancer patients in the Danish National Patient Registry.
Article in Clinical epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Osteonecrosis of the jaw and survival of patients with cancer: a nationwide cohort study in Denmark.Cancer medicine · 2017Article
- Helping everyone do better: a call for validation studies of routinely recorded health data.Clinical epidemiology · 2016Article
- Validation of algorithms to detect distant metastases in men with prostate cancer using routine registry data in Denmark.Clinical epidemiology · 2015Article
- The Danish National Patient Registry: a review of content, data quality, and research potential.Clinical epidemiology · 2015Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to estimate the positive predictive value (PPV) of the coding for bisphosphonate treatment in selected cancer patients from the Danish National Patient Registry (DNPR).
methodsThrough the DNPR, we identified all patients with recorded cancer of the breast, prostate, lung, kidney, and with multiple myeloma. We restricted the study sample to patients with bisphosphonate treatment recorded during an admission to Aalborg Hospital, Denmark, from 2005 through 2009. We retrieved and reviewed medical records of these patients from the initial cancer diagnosis onwards to confirm or rule out bisphosphonate therapy. We calculated the PPV of the treatment coding as the proportion of patients with confirmed bisphosphonate treatment.
resultsWe retrieved and reviewed the medical records of 60 cancer patients with treatment codes corresponding to bisphosphonate therapy. Recorded code corresponded to treatment administered intravenously for 59 of 60 patients, corresponding to a PPV of 98.3% (95% confidence interval 92.5-99.8). In the remaining patient, bisphosphonate treatment was also confirmed but was an orally administered bisphosphonate; thus, the treatment for any bisphosphonate regardless of administration was confirmed for all 60 patients (PPV of 100%, 95% confidence interval 95.9-100.0).
conclusionThe PPV of bisphosphonate treatment coding among cancer patients in the DNPR is very high and the recorded treatment nearly always corresponds to intravenous administration.
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