ArticlePlant physiology2012
Targeted systems biology profiling of tomato fruit reveals coordination of the Yang cycle and a distinct regulation of ethylene biosynthesis during postclimacteric ripening.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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52 citing papers in PubMed, 138 citations in OpenAlex.
- Ethylene networking in fruit ripening: molecular mechanisms, hormone crosstalk, climate interactions, and postharvest management.Plant cell reports · 2026Review
- A multi-perspective analysis of the regulatory mechanisms governing pedicel abscission in tomato.Plant cell reports · 2026Review
- ABA-ethylene crosstalk accelerates persimmon fruit softening via induction ofHorticulture research · 2026Article
- Sex-specific ethylene responses drive floral sexual plasticity in Cannabis sativa.The Plant journal : for cell and molecular biology · 2026Article
- Slow and steady wins the race: the negative regulators of ethylene biosynthesis in horticultural plants.Horticulture research · 2025Article
- Autophagy restricts tomato fruit ripening via a general role in ethylene repression.The New phytologist · 2025Article
- Plant Signaling Hormones and Transcription Factors: Key Regulators of Plant Responses to Growth, Development, and Stress.Plants (Basel, Switzerland) · 2025Review
- Genome-Wide In Silico Analysis of 1-Aminocyclopropane-1-carboxylate oxidase (ACO) Gene Family in Rice (Plants (Basel, Switzerland) · 2024Article
- The role of ethylene in the regulation of plant response mechanisms to waterlogging stress.Plant cell reports · 2024Review
- Exploring ethylene-related genes in Cannabis sativa: implications for sexual plasticity.Plant reproduction · 2024Article
- Plant Hormone Pathway Is Involved in Regulating the Embryo Development Mechanism of theInternational journal of molecular sciences · 2024Article
- Integrative Analysis of Metabolome and Transcriptome of Carotenoid Biosynthesis Reveals the Mechanism of Fruit Color Change in Tomato (International journal of molecular sciences · 2024Article
- The Potential of Essential Oils from Active Packaging to Reduce Ethylene Biosynthesis in Plant Products. Part 1: Vegetables (Broccoli and Tomato).Plants (Basel, Switzerland) · 2023Article
- Thorough Characterization ofFoods (Basel, Switzerland) · 2023Article
- A metabolome and transcriptome survey to tap the dynamics of fruit prolonged shelf-life and improved quality within Greek tomato germplasm.Frontiers in plant science · 2023Article
- Ethylene enhances resistance to cucumber green mottle mosaic virus via theFrontiers in plant science · 2023Article
- Targeted system approach to ethylene biosynthesis and signaling of a heat tolerant tomato cultivar; the impact of growing season on fruit ripening.Frontiers in plant science · 2023Article
- From a different angle: genetic diversity underlies differentiation of waterlogging-induced epinasty in tomato.Frontiers in plant science · 2023Article
- Article
- A molecular framework of ethylene-mediated fruit growth and ripening processes in tomato.The Plant cell · 2022Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concept of system 1 and system 2 ethylene biosynthesis during climacteric fruit ripening was initially described four decades ago. Although much is known about fruit development and climacteric ripening, little information is available about how ethylene biosynthesis is regulated during the postclimacteric phase. A targeted systems biology approach revealed a novel regulatory mechanism of ethylene biosynthesis of tomato (Solanum lycopersicum) when fruit have reached their maximal ethylene production level and which is characterized by a decline in ethylene biosynthesis. Ethylene production is shut down at the level of 1-aminocyclopropane-1-carboxylic acid oxidase. At the same time, 1-aminocyclopropane-1-carboxylic acid synthase activity increases. Analysis of the Yang cycle showed that the Yang cycle genes are regulated in a coordinated way and are highly expressed during postclimacteric ripening. Postclimacteric red tomatoes on the plant showed only a moderate regulation of 1-aminocyclopropane-1-carboxylic acid synthase and Yang cycle genes compared with the regulation in detached fruit. Treatment of red fruit with 1-methylcyclopropane and ethephon revealed that the shut-down mechanism in ethylene biosynthesis is developmentally programmed and only moderately ethylene sensitive. We propose that the termination of autocatalytic ethylene biosynthesis of system 2 in ripe fruit delays senescence and preserves the fruit until seed dispersal.
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