ArticleLangenbeck's archives of surgery2012
Hypocalcaemia after total thyroidectomy for Graves' disease and for benign atoxic multinodular goitre.
Article in Langenbeck's archives of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 48 citations in OpenAlex.
- Review
- The effect of preoperative vitamin D values on hypocalcemia after total thyroidectomy.Turkish journal of surgery · 2024Article
- Low serum iPTH at the end of surgery is the earliest predictor of postoperative hypocalcemia after total thyroidectomy.Langenbeck's archives of surgery · 2023Article
- Management of hypocalcemia following thyroid surgery in children.Frontiers in pediatrics · 2023Article
- Risk factors for difficult thyroidectomy and postoperative morbidity do not match: retrospective study from an endocrine surgery academic referral centre.Updates in surgery · 2022Article
- Adverse events in thyroid surgery: observational study in three surgical units with high volume/year.BMC surgery · 2021Observational
- Development and validation of a new model for predicting hypocalcaemia after total thyroidectomy: the NuGra model.Langenbeck's archives of surgery · 2021Article
- Can we still consider thyroid hyperfunction a protective condition for the onset of thyroid cancer?Gland surgery · 2021Article
- The Influence of Prophylactic Calcium and Magnesium Supplementation on Postoperative Quality of Life and Hypocalcemia After Total Thyroidectomy: Study Protocol for a Randomized Controlled Trial.Frontiers in surgery · 2021Article
- An evaluation score of the difficulty of thyroidectomy considering operating time and preservation of recurrent laryngeal nerve.Updates in surgery · 2019Article
- Correlation between iPTH Levels on the First Postoperative Day After Total Thyroidectomy and Permanent Hypoparathyroidism: Our Experience.Open medicine (Warsaw, Poland) · 2019Article
- Permanent Hypoparathyroidism After Total Thyroidectomy in Children: Results from a National Registry.World journal of surgery · 2018Article
- Rescue pre-operative treatment with Lugol's solution in uncontrolled Graves' disease.Endocrine connections · 2017Article
- Necessity of therapy for post-thyroidectomy hypocalcaemia: a multi-centre experience.Langenbeck's archives of surgery · 2015Observational
- Preventing postoperative hypocalcemia in patients with Graves disease: a prospective study.Annals of surgical oncology · 2015Article
- [Avoidance and management of hypoparathyroidism after thyroid gland surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2015Review
- Prediction of permanent hypoparathyroidism after total thyroidectomy.World journal of surgery · 2014Article
- Total thyroidectomy is associated with increased prevalence of permanent hypoparathyroidism.Medical science monitor : international medical journal of experimental and clinical research · 2014Article
- Identifying predictors of a difficult thyroidectomy.The Journal of surgical research · 2014Article
- Thyroidectomy as primary treatment optimizes body mass index in patients with hyperthyroidism.Annals of surgical oncology · 2014Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePostoperative hypocalcaemia has been reported to be more common after total thyroidectomy (TT) for Graves' disease than after TT for benign atoxic multinodular goitre (MNG). The reasons for this potential association are not clear. In the present study, the frequency and risk factors of hypocalcaemia after TT for Graves' vs MNG were compared.
methodsBetween January 1999 and October 2009, patients with first-time surgery for Graves' disease or MNG treated with a TT were included in the study. Postoperative hypocalcaemia was defined by symptoms, calcium levels and treatment with calcium and/or vitamin D analogues during postoperative hospital stay, at discharge, and at the 6-week and 6-month follow-ups. Outcomes were compared with Mann-Whitney, chi(2) and Fishers' exact test where appropriate and by multivariable logistic regression analysis.
resultsThere were 128 patients with Graves' disease and 81 patients with MNG. Patients with Graves' disease were younger than patients with MNG (median age, 35 vs 51 years, p < 0.001). Symptoms of hypocalcaemia were more common in patients with Graves' disease (p < 0.001; OR, 95 % CI 3.26, 1.48-7.14), but the frequency of biochemical hypocalcaemia, postoperative levels of parathyroid hormone (PTH) and treatment with calcium and vitamin D did not differ between groups of patients.
conclusionApart from more frequent symptoms of hypocalcaemia in patients with Graves' disease, there was no difference in the overall frequency of biochemical hypocalcaemia, low levels of PTH and/or treatment with calcium and vitamin D.
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