ArticleThe AAPS journal2012
Use of partial area under the curve metrics to assess bioequivalence of methylphenidate multiphasic modified release formulations.
Article in The AAPS journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Impact of release mechanism on the pharmacokinetic performance of PAUC metrics for three methylphenidate products with complex absorption.Pharmaceutical research · 2014Trial
- Partial Area Under the Curve: A Revelatory Story in Pharmacokinetics.Clinical pharmacokinetics · 2026Review
- A systematic approach to develop and characterize a compositionally equivalent buprenorphine in situ forming implant (Sublocade®).Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- The Role of Early Exposure Metrics (pAUCThe AAPS journal · 2025Article
- Double Peaking Phenomena in Pharmacokinetic Disposition Revisited.Clinical pharmacokinetics · 2025Review
- Methylphenidate Multiphasic Release Tablet: Bioequivalence Assessment between Two Formulations Administered under Fasting and Fed Conditions.Pharmaceutics · 2023Article
- An In Silico Approach toward the Appropriate Absorption Rate Metric in Bioequivalence.Pharmaceuticals (Basel, Switzerland) · 2023Article
- The Two Main Goals of Bioequivalence Studies.The AAPS journal · 2017Article
- Population pharmacokinetics of methylphenidate hydrochloride extended-release multiple-layer beads in pediatric subjects with attention deficit hyperactivity disorder.Drug design, development and therapy · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.