Evidence map›Paper›PMID 22976114›Full record

ArticleInternational journal of hematology2012

Unrelated cord blood transplantation for patients with adult T-cell leukemia/lymphoma: experience at a single institute.

Takayuki Nakamura, Eijiro Oku, Kei Nomura, Satoshi Morishige, Yuka Takata, Ritsuko Seki, Rie Imamura, Koichi Osaki, Michitoshi Hashiguchi, Kazuaki Yakushiji and 6 more

Abstract read
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In one paragraph

Article in International journal of hematology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Guideline
  2. Trial
  3. Trial
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Treatment advances and prognosis for patients with adult T-cell leukemia-lymphoma.Journal of clinical and experimental hematopathology : JCEH · 2017
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Takayuki NakamuraDivision of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
Eijiro Oku
Kei Nomura
Satoshi Morishige
Yuka Takata
Ritsuko Seki
Rie Imamura
Koichi Osaki
Michitoshi Hashiguchi
Kazuaki Yakushiji
Fumihiko Mouri
Shinichi Mizuno
Koji Yoshimoto
Koichi Ohshima
Koji Nagafuji
Takashi Okamura
Kurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the results of unrelated cord blood transplantation (UCBT) for patients with adult T-cell leukemia/lymphoma (ATLL) conducted in our single institute. Ten patients with ATLL (nine acute and one lymphoma-type) received UCBT during the period from August 2003 to July 2011. The median age at the time of diagnosis of ATLL was 51 years (range 37-64). The median period from diagnosis of ATLL to UCBT was 130 days (range 94-344). Conditioning regimens were myeloablative for six and reduced intensity for four. The median number of infused nucleated cells and CD34 positive cells were 2.52 × 10(7)/kg and 1.04 × 10(5)/kg, respectively. There was no engraftment failure. Three patients developed grade II acute graft versus host disease, and four developed grade III. The estimated 2-year overall survival was 40 % (95 % CI 12-67 %). Four of six chemosensitive patients prior to UCBT survived for 1035, 793, 712, and 531 days post-UCBT, respectively. There were no survivors among the four chemorefractory patients prior to UCBT. Our data indicates that UCBT is feasible and provides long-term survival in patients with chemosensitive ATLL.

Indexed as

Cord Blood Stem Cell TransplantationUnrelated DonorsAcute DiseaseAdultDisease-Free SurvivalFemaleGraft vs Host DiseaseHumansLeukemia-Lymphoma, Adult T-CellMaleMiddle AgedRetrospective StudiesSurvival RateTransplantation, Homologous

Identifiers

PMID22976114
OpenAlexW2084840837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.