Evidence map›Paper›PMID 22975001›Full record

ArticleCurrent biology : CB2012

Studies on Aplysia neurons suggest treatments for chronic human disorders.

Thomas W Abrams

Abstract read
In one paragraph

Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Host response to Aplysia Abyssovirus 1 in nervous system and gill.Developmental and comparative immunology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Enrofloxacin Pharmacokinetics and Sampling Techniques in California Sea Hares (Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  7. Article
  8. Modeling Fragile X Syndrome inFrontiers in molecular neuroscience · 2018
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Protein phosphatase-dependent circadian regulation of intermediate-term associative memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Thomas W AbramsDepartment of Pharmacology, Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201-1559, USA. tabrams@umaryland.edu

Funding

NONASSOCIATIVE AND ASSOCIATIVE NEUROPLASTICITYR01MH055880 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI ABRAMS, THOMAS W · 1995 to 2015
$4.9M
NIMH NIH HHS R01 MH055880
6 · The paper itself

Abstract

For decades, the marine snail Aplysia has proven to be a powerful system for analyzing basic neurobiological mechanisms, particularly cellular and molecular mechanisms of neural plasticity. Three new findings on Aplysia may be relevant for the understanding and treatment of chronic human disorders. This research on this simple molluscan nervous system may lead to new therapeutic approaches for spinal cord injury, Fragile X syndrome, and genetic learning deficits more generally.

Indexed as

Computer SimulationModels, NeurologicalAnimalsAplysiaFragile X SyndromeHumansLearning DisabilitiesNervous System Physiological PhenomenaNeuronal PlasticityNeuronsSignal TransductionSpinal Cord Injuries

Identifiers

PMID22975001
PMCPMC9279012

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.