ReviewInternational journal of experimental pathology2012
Heterotopic mineralization (ossification or calcification) in tendinopathy or following surgical tendon trauma.
Review in International journal of experimental pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
63 citing papers in PubMed, 126 citations in OpenAlex.
- PRMT6 is required for initiating and amplifying macrophage-induced inflammation in heterotopic ossification by increasing CCL2 expression.Bone research · 2026Article
- POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A CD26Nature communications · 2025Article
- Denervation‑induced NRG3 aggravates muscle heterotopic ossification via the ErbB4/PI3K/Akt signaling pathway.Molecular medicine reports · 2025Article
- Integrated transcriptomic analysis reveals evolutionary and developmental characteristics of tendon ossification in teleost.BMC biology · 2024Article
- Article
- Early arthroscopic debridement of posterior cruciate ligament calcification after symptom presentation led to immediate recovery: a case report.BMC musculoskeletal disorders · 2024Article
- Elemental and Structural Characterization of Heterotopic Ossification during Achilles Tendon Healing Provides New Insights on the Formation Process.ACS biomaterials science & engineering · 2024Article
- Animal models of tendon calcification: Past, present, and future.Animal models and experimental medicine · 2024Review
- Immunologic Aspects in Fibrodysplasia Ossificans Progressiva.Biomolecules · 2024Review
- Metformin alleviates genetic and traumatic heterotopic ossification by inhibiting infiltration and mitochondrial metabolism of myeloid cells.American journal of translational research · 2024Article
- Tenosynovitis With Psammomatous Calcification Preoperatively Diagnosed as Intra-Articular Free Body of the Young Male Wrist: A Case Report.Journal of hand surgery global online · 2023Article
- Review
- Nanomaterials for Periodontal Tissue Regeneration: Progress, Challenges and Future Perspectives.Journal of functional biomaterials · 2023Review
- MiRNAs as Potential Regulators of Enthesis Healing: Findings in a Rodent Injury Model.International journal of molecular sciences · 2023Article
- Targeting Senescent Tendon Stem/Progenitor Cells to Prevent or Treat Age-Related Tendon Disorders.Stem cell reviews and reports · 2023Review
- Article
- Heterotopic mineral deposits in intact rat Achilles tendons are characterized by a unique fiber-like structure.Journal of structural biology: X · 2023Article
- Contemporary perspectives on heterotopic ossification.JCI insight · 2022Review
- Enthesis Healing Is Dependent on Scaffold Interphase Morphology-Results from a Rodent Patellar Model.Cells · 2022Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heterotopic tendon mineralization (ossification or calcification), which may be a feature of tendinopathy or which may develop following surgical trauma (repair or graft harvest), has not received much attention. The purpose of this article is to review the prevalence, mechanisms and consequences of heterotopic tendon mineralization and to identify the gaps in our current understanding. We focus on endochondral heterotopic ossification and draw on knowledge of the mechanisms of this process in other tissues and conditions. Finally, we introduce a novel murine Achilles tendon needle injury model, which will enable us to further study the mechanisms and biomechanical consequences of tendon mineralization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.