ArticleTherapeutic advances in gastroenterology2012
Pain management in patients with inflammatory bowel disease: insights for the clinician.
Article in Therapeutic advances in gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease.The Cochrane database of systematic reviews · 2021Pooled it
- Interventions for the management of abdominal pain in ulcerative colitis.The Cochrane database of systematic reviews · 2021Pooled it
- Patient views about the impact of ulcerative colitis and its management with drug treatment and surgery: a nested qualitative study within the CONSTRUCT trial.BMC gastroenterology · 2019Trial
- Article
- Targeting γ-aminobutyric acid pathways in irritable bowel syndrome: bridging central nervous system, enteric dysfunction, and the microbiota-gut-brain axis.Frontiers in pharmacology · 2025Review
- Abdominal Pain in Inflammatory Bowel Disease-Epidemiology, Pathophysiology, and Management: A Narrative Review.Pain and therapy · 2024Review
- Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study.Molecular brain · 2024Article
- Evaluation of the beneficial effects of a GABA-based product containingFrontiers in pharmacology · 2024Article
- Unveiling the efficacy of paroxetine and gabapentin in ulcerative colitis patients in remission with co-existing IBS-like symptoms: a single-blinded randomized clinical trial.Frontiers in medicine · 2024Article
- Chronic abdominal pain in inflammatory bowel disease: a practical guide.Frontline gastroenterology · 2024Review
- Opioid use in children with inflammatory bowel disease-related arthritis.Clinical and experimental rheumatology · 2023Article
- New Insights into the Mechanism ofMarine drugs · 2023Article
- Management of Pelvic Pain in Patients with Crohn's Disease-Current Overview.Journal of clinical medicine · 2023Review
- IBD-related mental health disorders: where do we go from here?Frontline gastroenterology · 2023Review
- Medicaid Analysis of Substances of Abuse for Patients With Crohn's Disease.Gastro hep advances · 2023Article
- Medication use among patients with Crohn's disease or ulcerative colitis before and after the initiation of advanced therapy.BMC gastroenterology · 2022Observational
- Appraisals of Pain in Pediatric Inflammatory Bowel Disease: A Qualitative Study With Youth, Parents, and Providers.Crohn's & colitis 360 · 2022Article
- The Efficacy ofNutrients · 2022Article
- Abdominal Pain in Inflammatory Bowel Diseases: A Clinical Challenge.Journal of clinical medicine · 2022Review
- Supraspinal Mechanisms of Intestinal Hypersensitivity.Cellular and molecular neurobiology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abdominal pain is a common symptom in patients with inflammatory bowel disease (IBD) and has a profound negative impact on patients' lives. There are growing data suggesting that pain is variably related to the degree of active inflammation. Given the multifactorial etiologies underlying the pain, the treatment of abdominal pain in the IBD population is best accomplished by individualized plans. This review covers four clinically relevant categories of abdominal pain in patients with IBD, namely, inflammation, surgical complications, bacterial overgrowth, and neurobiological processes and how pain management can be addressed in each of these cases. The role of genetic factors, psychological factors, and psychosocial stress in pain perception and treatment will also be addressed. Lastly, psychosocial, pharmacological, and procedural pain management techniques will be discussed. An extensive review of the existing literature reveals a paucity of data regarding pain management specific to IBD. In addition, there is growing consensus suggesting a spectrum between IBD and irritable bowel syndrome (IBS) symptoms. Thus, this review for adult and pediatric clinicians also incorporates the literature for the treatment of functional abdominal pain and the clinical consensus from IBD and IBS experts on pharmacological, behavioral, and procedural methods to treat abdominal pain in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.