ArticleEvidence-based complementary and alternative medicine : eCAM2012
The effects of tualang honey on bone metabolism of postmenopausal women.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Network pharmacological insight into traditional bone healing practices of Sikkim, India.PloS one · 2026Article
- Effects of Aerobic Dance Exercise and Honey Supplementation Followed by Their Subsequent Cessation on Bone Metabolism Markers and Antioxidant Status in Young Collegiate Females.The Malaysian journal of medical sciences : MJMS · 2023Article
- Honey: A Promising Therapeutic Supplement for the Prevention and Management of Osteoporosis and Breast Cancer.Antioxidants (Basel, Switzerland) · 2023Review
- Antioxidative and Anti-Inflammatory Activities of Chrysin and Naringenin in a Drug-Induced Bone Loss Model in Rats.International journal of molecular sciences · 2022Article
- A chitosan film containing quercetin-loaded transfersomes for treatment of secondary osteoporosis.Drug delivery and translational research · 2020Article
- Honey as an antioxidant therapy to reduce cognitive ageing.Iranian journal of basic medical sciences · 2019Review
- Protective effects of honey by bees (Veterinary world · 2019Article
- Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines.Journal of biomedical science · 2014Article
- Comparison on the Effects and Safety of Tualang Honey and Tribestan in Sperm Parameters, Erectile Function, and Hormonal Profiles among Oligospermic Males.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Tualang honey improves human corneal epithelial progenitor cell migration and cellular resistance to oxidative stress in vitro.PloS one · 2014Article
- Cinnamomum burmanini Blume increases bone turnover marker and induces tibia's granule formation in ovariectomized rats.Journal of Ayurveda and integrative medicineArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoporosis which is characterized by low bone mass and microarchitectural deterioration with a consequent increase in bone fragility can be associated with various stimuli such as oxidative stress and inflammation. Postmenopausal women are more prone to osteoporosis due to reduction in estrogen which may further lead to elevation of oxidative stress and lipid accumulation which will promote osteoblasts apoptosis. Proinflammatory cytokines are elevated following estrogen deficiency. These cytokines are important determinants of osteoclasts differentiation and its bone resorption activity. The main treatment for postmenopausal osteoporosis is estrogen replacement therapy (ERT). Despite its effectiveness, ERT, however, can cause many adverse effects. Therefore, alternative treatment that is rich in antioxidant and can exert an anti-inflammatory effect can be given to replace the conventional ERT. Tualang honey is one of the best options available as it contains antioxidant as well as exerting anti-inflammatory effect which can act as a free radical scavenger, reducing the oxidative stress level as well as inhibiting proinflammatory cytokine. This will result in survival of osteoblasts, reduced osteoclastogenic activity, and consequently, reduce bone loss. Hence, Tualang honey can be used as an alternative treatment of postmenopausal osteoporosis with minimal side effects.
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Registered trials
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