ArticleEvidence-based complementary and alternative medicine : eCAM2012
Antibacterial Activity of Rhodomyrtus tomentosa (Aiton) Hassk. Leaf Extract against Clinical Isolates of Streptococcus pyogenes.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Antibacterial and Anti-Inflammatory Activity of Chitosan Film with Rhodomyrtus Tomentosa Leaf Extract Prepared Via 3D-Printing Method.ChemistryOpen · 2025Article
- Rhodomyrtone-rich fractions fromVeterinary world · 2025Article
- Next-generation sequencing-based population genetics unravels the evolutionary history of Rhodomyrtus tomentosa in China.BMC plant biology · 2025Article
- The Diverse Activities and Mechanisms of the Acylphloroglucinol Antibiotic Rhodomyrtone: Antibacterial Activity and Beyond.Antibiotics (Basel, Switzerland) · 2024Review
- The Health Beneficial Properties ofBiomolecules · 2019Review
- The novel antibiotic rhodomyrtone traps membrane proteins in vesicles with increased fluidity.PLoS pathogens · 2018Article
- Integrated proteomic and metabolomic analysis reveals that rhodomyrtone reduces the capsule in Streptococcus pneumoniae.Scientific reports · 2017Article
- Potential Bio-Control Agent from Rhodomyrtus tomentosa against Listeria monocytogenes.Nutrients · 2015Article
- Inhibitory activity of Myrtus communis oil on some clinically isolated oral pathogens.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethanol extract of Rhodomyrtus tomentosa (Aiton) Hassk. leaf was evaluated for antibacterial activity against 47 clinical isolates of Streptococcus pyogenes. The extract exhibited good anti-S. pyogenes activity against all the tested isolates with similar minimum inhibitory concentration (MIC, 3.91-62.5 μg mL(-1)) and minimum bactericidal concentration (MBC, 3.91-62.5 μg mL(-1)) ranges. No surviving cells were detected at 16 h after treatment with 8 × MIC of the extract. The extract-treated cells demonstrated no lysis and cytoplasmic leakage through the bacterial membrane. Electron micrographs further revealed that the extract did not cause any dramatic changes on the treated cells. Rhodomyrtone, an isolated compound, exhibited good anti-S. pyogenes activity (14 isolates), expressed very low MIC (0.39-1.56 μg mL(-1)) and MBC (0.39-1.56 μg mL(-1)) values. Rhodomyrtus tomentosa leaf extract and rhodomyrtone displayed promising antibacterial activity against clinical isolates of S. pyogenes.
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Registered trials
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