ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2011
An Iranian experience on renal allograft diseases.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- The causes and frequency of kidney allograft failure in a low-resource setting: observational data from Iraqi Kurdistan.BMC nephrology · 2021Observational
- Pathological assessment of allograft nephrectomy: An Iranian experience.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundRenal transplantation is the treatment of choice for most patients with end stage renal disease. In addition, renal biopsy is the gold standard to assess the causes of renal allograft dysfunction. This study was designed to evaluate and designate renal lesions according to Banff schema.
methodsIn this cross-sectional study, all renal allograft biopsies obtained from renal transplant patients at Alzahra and Noor referral hospitals in Isfahan during 2006-2008 were studied. Evaluations were made according to the Banff classification 2009. Clinical data was collected from the pathology database and analyzed using SPSS.
resultsA total number of 161 specimens were studied from 68% male and 32% female subjects. The donor source was living unrelated in 85%, living related 9.9% and cadaveric in 5% of cases. Pathologic results showed 22.4% acute tubular necrosis (ATN), 13.7% interstitial fibrosis and tubular atrophy (IF/TA) grade II, 9.9% IF/TA (Grade III), 6.8% acute T-cell mediated rejection (TCMR-IA), 5.6% TCMR-IB, 5% borderline change, 5% infarction, 4.3% TCMR-IIA, 4.3% TA/IF (Grade I), 3.7% acute antibody-mediated rejection (ABMR), 1.9% TCMR-IIB and 17.4% other lesions.
conclusionsThe commonest causes of graft dysfunction after kidney transplant were IF/TA, no evidence of any specific etiology (NOS) and ATN. Living donors were found to be important sources for kidney transplantation in Iran.
Indexed as
Identifiers
22973365PMC3434898W2146485889What OpenQuestion holds
Registered trials
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