ReviewCurrent hypertension reports2012
Heart rate and blood pressure: any possible implications for management of hypertension?
Review in Current hypertension reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06450327 (Resistant Hypertension An Open, Complicated), which is not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Resistant Hypertension An Open, Complicated ("Cum Plicare") or Complex ("Cum Plexus")
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Gender correlation between sleep duration and risk of coronary heart disease: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Benefits of continuous positive airway pressure on blood pressure in patients with hypertension and obstructive sleep apnea: a meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Pooled it
- Variability in home blood pressure and its association with renal function and pulse pressure in patients with treated hypertension in primary care.Journal of human hypertension · 2024Trial
- Predicting blood pressure from physiological index data using the SVR algorithm.BMC bioinformatics · 2019Trial
- Association of resting heart rate trajectories with incident chronic kidney disease in patients with hypertension.Clinical hypertension · 2026Article
- Cardiopulmonary Benefits of Exercise in Adolescents.Advances in experimental medicine and biology · 2026Review
- The Impact of Digital Intervention Messages Targeting Users With High Blood Pressure Events: Retrospective Real-World Study.JMIR cardio · 2025Article
- BEAT-HTN India: Burden, Epidemiology, and Trends of Hypertension - A Nationwide Survey.Cardiology research · 2025Article
- Effect of N-Acetylcysteine in Mitochondrial Function, Redox Signaling, and Sirtuin 3 Levels in the Heart During Cardiorenal Syndrome Type 4 Development.Antioxidants (Basel, Switzerland) · 2025Article
- One-week test-retest recordings of resting cardiorespiratory data for reliability analysis.Scientific data · 2025Article
- High Resting Heart Rate Is Associated with Cardiovascular Death in Patients with Stroke, Independent of Sex.Cerebrovascular diseases (Basel, Switzerland) · 2025Article
- Detection of hypertension from pharyngeal images using deep learning algorithm in primary care settings in Japan.BMJ health & care informatics · 2024Article
- Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort.iScience · 2024Article
- Do Photopletysmographic Parameters of Arterial Stiffness Differ Depending on the Presence of Arterial Hypertension and/or Atherosclerosis?Sensors (Basel, Switzerland) · 2024Article
- The Association between the JAK-STAT Pathway and Hypertension among Kenyan Women Diagnosed with Breast Cancer.bioRxiv : the preprint server for biology · 2024Article
- Rosuvastatin, but not atorvastatin, enhances the antihypertensive effect of cilostazol in an acute model of hypertension.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- [Prevalence and Influencing Factors of Isolated Diastolic Hypertension in Tibetan Population in Tibet].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Effect of exercise based on ACSM recommendations on blood pressure and heart rate in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials.PLOS global public health · 2024Article
- Insulin resistance, C-reactive protein, diastolic to systolic blood pressure ratio and epicardial fat are related to sedentary time, and inversely related to physical activity in school-aged children.Frontiers in public health · 2024Article
- Resting Heart Rate Independent of Cardiovascular Disease Risk Factors Is Associated With End-Stage Renal Disease: A Cohort Study Based on 476 347 Adults.Journal of the American Heart Association · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Hypertension is a common clinical problem and a major risk factor for cardiovascular disease and stroke. Elevated heart rate is associated with elevated blood pressure, increased risk for hypertension, and, among hypertensives, increased risk for cardiovascular disease. Despite these important relationships, heart rate is generally not a major consideration in choosing antihypertensive medications. In part, this is due to a lack of evidence supporting heart rate lowering as a therapeutic strategy in hypertension. Additionally, while there is a positive correlation between heart rate and peripheral blood pressure, there is an inverse relationship between heart rate and central blood pressure. The use of antihypertensive medications, specifically medications that affect heart rate, may not reliably reduce central blood pressure to a similar extent as observed peripherally. We review the relationship between heart rate and peripheral and central blood pressure, with a focus on the implications for chronotropic therapy in hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.