Evidence map›Paper›PMID 22972497›Full record

ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2013

Post-therapeutic surveillance strategies in head and neck squamous cell carcinoma.

Antoine Digonnet, Marc Hamoir, Guy Andry, Missak Haigentz, Robert P Takes, Carl E Silver, Dana M Hartl, Primož Strojan, Alessandra Rinaldo, Remco de Bree and 12 more

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Guideline
  2. Diagnostic value of MRI for posttreatment surveillance of early-stage (I-II) glottic larynx cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  3. Review
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  10. Metastatic disease in head & neck oncology.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2020
    Review
  11. Article
  12. Article
  13. Performance of whole-bodyEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 17 institutions in 9 countries.

Antoine DigonnetDepartment of Head and Neck and Thoracic Surgery, Institut Jules Bordet, Brussels, Belgium.
Marc Hamoir
Guy Andry
Missak Haigentz
Robert P Takes
Carl E Silver
Dana M Hartl
Primož Strojan
Alessandra Rinaldo
Remco de Bree
Andreas Dietz
Vincent Grégoire
Vinidh Paleri
Johannes A Langendijk
Vincent Vander Poorten
Michael L Hinni
Juan P Rodrigo
Carlos Suárez
William M Mendenhall
Jochen A Werner
Eric M Genden
Alfio Ferlito
Institut Jules Bordet · BEInstituto de Investigación Sanitaria del Principado de Asturias · ESMontefiore Medical Center · USUniversity of Udine · ITAmsterdam UMC Location Vrije Universiteit Amsterdam · NLInstitute of Oncology Ljubljana · SIKU Leuven · BELaboratoire de Phonétique et Phonologie · FRLeipzig University · DEMayo Clinic Hospital · USMount Sinai Medical Center · USNewcastle upon Tyne Hospitals NHS Foundation Trust · GBPhilipps University of Marburg · DERadboud University Nijmegen · NLUCLouvain · BEUniversity Medical Center Groningen · NLUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of head and neck squamous cell carcinomas does not end with the completion of ablative therapy. The oncologic objectives of post-treatment follow-up are to detect recurrences and second primary tumors; beyond that, follow-up should evaluate acute and chronic treatment-related side effects, guide the rehabilitation process, alleviate functional loss, manage pain, restore nutritional status and assess psychosocial factors. In this structured review, we address the questions of timing and the tools required to achieve a complete and coherent routine surveillance. Several guidelines and consensus statements recommend clinical examination as the cornerstone of follow-up which should be performed for at least 5 years, although there are no data in favor of any one particular follow-up program, and only low-level evidence suggests an improvement in oncologic outcomes by close follow-up. Baseline imaging (computed tomography and magnetic resonance imaging) should be obtained within 2-6 months after definitive therapy if used for treatment response evaluation. Metabolic response, if indicated, should be assessed preferably after 3 months in patients who undergo curative-intent therapy with (chemo)-radiotherapy. Chest computed tomography is more sensitive than plain radiography, if used in follow-up, but the benefit and cost-effectiveness of routine chest computed tomography has not been demonstrated. There are no current data supporting modifications specific to the surveillance plan of patients with human papillomavirus-associated disease.

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsHumansMagnetic Resonance ImagingMultimodal ImagingNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasms, Second PrimarySquamous Cell Carcinoma of Head and NeckTime FactorsTomography, X-Ray Computed

Identifiers

PMID22972497
OpenAlexW2154702512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.