ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2013
Expression of genes involved in energy mobilization and osmoprotectant synthesis during thermal and dehydration stress in the Antarctic midge, Belgica antarctica.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Effects of water temperature on freshwater macroinvertebrates: a systematic review.Biological reviews of the Cambridge Philosophical Society · 2023Pooled it
- Molecular mechanisms and energetic costs of recovery from freezing in the polyextremophile midge Belgica antarctica.The Journal of experimental biology · 2026Article
- Temperature changes reveal different transcriptional responses in the larvae of the bark beetle Dendroctonus rhizophagus during the cold season.Scientific reports · 2026Article
- Article
- From whole bodies to single cells: A guide to transcriptomic approaches for ecology and evolutionary biology.Molecular ecology · 2025Review
- Trends and Emerging Hotspots in Toxicology of Chironomids: A Comprehensive Bibliometric Analysis.Insects · 2025Article
- Dehydration Dynamics in Terrestrial Arthropods: From Water Sensing to Trophic Interactions.Annual review of entomology · 2023Review
- Using Proteomic Approaches to Unravel the Response ofFrontiers in cellular and infection microbiology · 2022Article
- Multi-level analysis of reproduction in an Antarctic midge identifies female and male accessory gland products that are altered by larval stress and impact progeny viability.Scientific reports · 2020Article
- Characterization of Gromphadorhina coquereliana hemolymph under cold stress.Scientific reports · 2020Article
- Changes in Energy Reserves and Gene Expression Elicited by Freezing and Supercooling in the Antarctic Midge,Insects · 2019Article
- TDCIPP exposure affects Artemia franciscana growth and osmoregulation.The Science of the total environment · 2019Article
- Review
- Transcriptome profiling illustrates expression signatures of dehydration tolerance in developing grasspea seedlings.Planta · 2019Article
- Evaluating sub-lethal stress from RoundupAquatic toxicology (Amsterdam, Netherlands) · 2019Article
- Overexpression of an antioxidant enzyme improves male mating performance after stress in a lek-mating fruit fly.Proceedings. Biological sciences · 2019Article
- Functional characterization of theFrontiers in zoology · 2018Article
- iTRAQ-Based Quantitative Proteomic Analysis of Spirulina platensis in Response to Low Temperature Stress.PloS one · 2016Article
- Global transcriptional dynamics of diapause induction in non-blood-fed and blood-fed Aedes albopictus.PLoS neglected tropical diseases · 2015Article
- Transcriptome characterization analysis of Bactrocera minax and new insights into its pupal diapause development with gene expression analysis.International journal of biological sciences · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Antarctic midge, Belgica antarctica, experiences sub-zero temperatures and desiccating conditions for much of the year, and in response to these environmental insults, larvae undergo rapid shifts in metabolism, mobilizing carbohydrate energy reserves to promote synthesis of low-molecular-mass osmoprotectants. In this study, we measured the expression of 11 metabolic genes in response to thermal and dehydration stress. During both heat and cold stress, we observed upregulation of phosphoenolpyruvate carboxykinase (pepck) and glycogen phosphorylase (gp) to support rapid glucose mobilization. In contrast, there was a general downregulation of pathways related to polyol, trehalose, and proline synthesis during both high- and low-temperature stress. Pepck was likewise upregulated in response to different types of dehydration stress; however, for many of the other genes, expression patterns depended on the nature of dehydration stress. Following fast dehydration, expression patterns were similar to those observed during thermal stress, i.e., upregulation of gp accompanied by downregulation of trehalose and proline synthetic genes. In contrast, gradual, prolonged dehydration (both at a constant temperature and in conjunction with chilling) promoted marked upregulation of genes responsible for trehalose and proline synthesis. On the whole, our data agree with known metabolic adaptations to stress in B. antarctica, although a few discrepancies between gene expression patterns and downstream metabolite contents point to fluxes that are not controlled at the level of transcription.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.