Evidence map›Paper›PMID 22972103›Full record

SynthesisThe Cochrane database of systematic reviews2012

Interventions for preventing falls in older people living in the community.

Lesley D Gillespie, M Clare Robertson, William J Gillespie, Catherine Sherrington, Simon Gates, Lindy M Clemson, Sarah E Lamb

13 registry-linked trialsOpen access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 13 registered trials, which are not on this map. Cited by 1,259 papers, 28 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,259citing papers in PubMed, 28 pooled it
567.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02419768 naunknown statusnot on this mapstarted 2014, after this paper: background citation

Locomotion of Parkinsonian Patient: Are There Relations Between the Long Range Autocorrelations and the Neurological Impairments, Walking Abilities and the Practice of Physical Exercise?

TypeinterventionalSponsorCliniques universitaires Saint-Luc- Université Catholique de LouvainRan2014Enrolled50ConditionsParkinson's DiseaseArmsPhysical Exercise
NCT02443038 nacompletednot on this mapstarted 2014, after this paper: background citation

Yoga's Effect on Fall Risk Factors in the Rural, Older Adult Population; an Academic/Community Partnership

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2014 to 2016Enrolled43ConditionsPatient FallArmsYoga
NCT02570178 nacompletednot on this map

Randomized Clinical Trial Evaluating the Effectiveness of a Primary Care Intervention Using the NintendoTM Wii Console to Improve Balance and Decrease Falls in the Elderly (EWii)

TypeinterventionalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2012 to 2016Enrolled1,037ConditionsPostural Balance, Accidental Falls, Intervention StudiesArmsbalance training
NCT03545529 nacompletednot on this mapstarted 2018, after this paper: background citation

Medico-economic Assessment of a "IsereADOM" Package of Services Versus Conventional Monitoring in the Care of a Population of Frail Elderly People With Loss of Autonomy.

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2018 to 2019Enrolled14ConditionsFall PatientsArmsInnovativ supported
NCT03592420 nacompletednot on this mapstarted 2014, after this paper: background citation

Efficacy of a Multifactorial and Personalized Program for Fall Prevention in Community-dwelling Elderly in Comparison to the Usual Care: a Randomized Controlled Trial

TypeinterventionalSponsorAzienda Unita' Sanitaria Locale Di ModenaRan2014 to 2017Enrolled366ConditionsFall, Aging, Parkinson Disease, StrokeArmsInterdisciplinary multicomponent interventions, Usual care
NCT04801316 naterminatednot on this mapstarted 2021, after this paper: background citation

Steady Feet: Proof of Value

TypeinterventionalSponsorChangi General HospitalRan2021 to 2022Enrolled154ConditionsCommunity-dwelling Older Adults, Fall RiskArmsSteady Feet exercise programme, Steady Feet Video
NCT05091671 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Investigating the Effectiveness of the "Free From Pain" Exercise and Education Programme in Decreasing Early Osteoarthritic / Generalised Musculoskeletal Pain in People Over 60 Years of Age

TypeinterventionalSponsorTalita Cumi Ltd.Ran2023 to 2023Enrolled60ConditionsMusculoskeletal Pain, Fear of FallingArmsFree From Pain Exercise Programme Variation 1, Free From Pain Exercise Programme Variation 2
NCT05541432 nacompletednot on this mapstarted 2022, after this paper: background citation

Finding the Optimal Resistance Training Intensity For Your Bones: A Randomized Controlled Trial (FORTIFY Bones)

TypeinterventionalSponsorUniversity of WaterlooRan2022 to 2026Enrolled324ConditionsOsteoporosis, OsteopeniaArmsSupervised strength training (group 1), Supervised strength training (group 2), Home exercise
NCT05682872 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Multifactorial Fall Prevention Program in People Aged 65 or Over of an Urban Area of Talavera de la Reina

TypeinterventionalSponsorCastilla-La Mancha Health ServiceRan2021 to 2026Enrolled264ConditionsFrail Elderly SyndromeArmsPhysical exercise program (VIVIFRAIL) supervised by a physiotherapist, Adequacy of the environment, Polypharmacy review, Health education related to falls prevention (4 sessions), General Assement
NCT06345118 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluate the Results of Fall Prevention in Older Adults With Type 2 Diabetes Mellitus

TypeinterventionalSponsorNational Geriatric HospitalRan2024 to 2025Enrolled80ConditionsDiabetes Mellitus, Type 2, Fall, Elderly PatientArmsOtago exercise program
NCT06891014 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Regular Exercise on Sensory-motor Functions and Fall Risk in the Elderly

TypeinterventionalSponsorCyprus International UniversityRan2024 to 2024Enrolled92ConditionsFall Risk, Exercise, Functional Outcomes, AgingArmsCombine Exercise
NCT06961812 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Validation of the Self-Assessment for Falls in the Elderly (SAFE) Questionnaire to Assess the Risk of Falls in People Aged 60 or Over.

TypeinterventionalSponsorUniversity Hospital, MontpellierRan2025 to 2026Enrolled300ConditionsFall Prevention, Falls (Accidents) in Old AgeArmsQuestionnaire and Physical Exam, Safe Self-Administered Questionnaire
NCT07092176 narecruitingnot on this mapstarted 2026, after this paper: background citation

Randomized Controlled Study on Fall Prevention in Community-Dwelling Older Adults: Physiatry Based Steady Strides Intervention vs Primary Care

TypeinterventionalSponsorSteady Strides: Fall Prevention and Stroke Rehabilitation Medical InstituteRan2026 to 2029Enrolled102ConditionsFall Prevention, FallsArmsSteady Strides
3 · Its place in the literature

Who cites it

1,259 citing papers in PubMed, 28 syntheses or guidelines pooled it, 3,911 citations in OpenAlex.

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1,199 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 3 countries.

Lesley D GillespieDepartment of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand. lesley.gillespie@otago.ac.nz.
M Clare Robertson
William J Gillespie
Catherine Sherrington
Simon Gates
Lindy M Clemson
Sarah E Lamb
Cancer Research UK Clinical Trials Unit · GBHull York Medical School · GBInstitute for Musculoskeletal Health · AUNuffield Orthopaedic Centre · GBUniversity of Manchester · GBUniversity of Otago · NZUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApproximately 30% of people over 65 years of age living in the community fall each year. This is an update of a Cochrane review first published in 2009.

objectivesTo assess the effects of interventions designed to reduce the incidence of falls in older people living in the community. SEARCH

methodsWe searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (February 2012), CENTRAL (The Cochrane Library 2012, Issue 3), MEDLINE (1946 to March 2012), EMBASE (1947 to March 2012), CINAHL (1982 to February 2012), and online trial registers. SELECTION CRITERIA: Randomised trials of interventions to reduce falls in community-dwelling older people. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed risk of bias and extracted data. We used a rate ratio (RaR) and 95% confidence interval (CI) to compare the rate of falls (e.g. falls per person year) between intervention and control groups. For risk of falling, we used a risk ratio (RR) and 95% CI based on the number of people falling (fallers) in each group. We pooled data where appropriate. MAIN

resultsWe included 159 trials with 79,193 participants. Most trials compared a fall prevention intervention with no intervention or an intervention not expected to reduce falls. The most common interventions tested were exercise as a single intervention (59 trials) and multifactorial programmes (40 trials). Sixty-two per cent (99/159) of trials were at low risk of bias for sequence generation, 60% for attrition bias for falls (66/110), 73% for attrition bias for fallers (96/131), and only 38% (60/159) for allocation concealment.Multiple-component group exercise significantly reduced rate of falls (RaR 0.71, 95% CI 0.63 to 0.82; 16 trials; 3622 participants) and risk of falling (RR 0.85, 95% CI 0.76 to 0.96; 22 trials; 5333 participants), as did multiple-component home-based exercise (RaR 0.68, 95% CI 0.58 to 0.80; seven trials; 951 participants and RR 0.78, 95% CI 0.64 to 0.94; six trials; 714 participants). For Tai Chi, the reduction in rate of falls bordered on statistical significance (RaR 0.72, 95% CI 0.52 to 1.00; five trials; 1563 participants) but Tai Chi did significantly reduce risk of falling (RR 0.71, 95% CI 0.57 to 0.87; six trials; 1625 participants).Multifactorial interventions, which include individual risk assessment, reduced rate of falls (RaR 0.76, 95% CI 0.67 to 0.86; 19 trials; 9503 participants), but not risk of falling (RR 0.93, 95% CI 0.86 to 1.02; 34 trials; 13,617 participants).Overall, vitamin D did not reduce rate of falls (RaR 1.00, 95% CI 0.90 to 1.11; seven trials; 9324 participants) or risk of falling (RR 0.96, 95% CI 0.89 to 1.03; 13 trials; 26,747 participants), but may do so in people with lower vitamin D levels before treatment.Home safety assessment and modification interventions were effective in reducing rate of falls (RR 0.81, 95% CI 0.68 to 0.97; six trials; 4208 participants) and risk of falling (RR 0.88, 95% CI 0.80 to 0.96; seven trials; 4051 participants). These interventions were more effective in people at higher risk of falling, including those with severe visual impairment. Home safety interventions appear to be more effective when delivered by an occupational therapist.An intervention to treat vision problems (616 participants) resulted in a significant increase in the rate of falls (RaR 1.57, 95% CI 1.19 to 2.06) and risk of falling (RR 1.54, 95% CI 1.24 to 1.91). When regular wearers of multifocal glasses (597 participants) were given single lens glasses, all falls and outside falls were significantly reduced in the subgroup that regularly took part in outside activities. Conversely, there was a significant increase in outside falls in intervention group participants who took part in little outside activity.Pacemakers reduced rate of falls in people with carotid sinus hypersensitivity (RaR 0.73, 95% CI 0.57 to 0.93; three trials; 349 participants) but not risk of falling. First eye cataract surgery in women reduced rate of falls (RaR 0.66, 95% CI 0.45 to 0.95; one trial; 306 participants), but second eye cataract surgery did not.Gradual withdrawal of psychotropic medication reduced rate of falls (RaR 0.34, 95% CI 0.16 to 0.73; one trial; 93 participants), but not risk of falling. A prescribing modification programme for primary care physicians significantly reduced risk of falling (RR 0.61, 95% CI 0.41 to 0.91; one trial; 659 participants).An anti-slip shoe device reduced rate of falls in icy conditions (RaR 0.42, 95% CI 0.22 to 0.78; one trial; 109 participants). One trial (305 participants) comparing multifaceted podiatry including foot and ankle exercises with standard podiatry in people with disabling foot pain significantly reduced the rate of falls (RaR 0.64, 95% CI 0.45 to 0.91) but not the risk of falling.There is no evidence of effect for cognitive behavioural interventions on rate of falls (RaR 1.00, 95% CI 0.37 to 2.72; one trial; 120 participants) or risk of falling (RR 1.11, 95% CI 0.80 to 1.54; two trials; 350 participants).Trials testing interventions to increase knowledge/educate about fall prevention alone did not significantly reduce the rate of falls (RaR 0.33, 95% CI 0.09 to 1.20; one trial; 45 participants) or risk of falling (RR 0.88, 95% CI 0.75 to 1.03; four trials; 2555 participants).No conclusions can be drawn from the 47 trials reporting fall-related fractures.Thirteen trials provided a comprehensive economic evaluation. Three of these indicated cost savings for their interventions during the trial period: home-based exercise in over 80-year-olds, home safety assessment and modification in those with a previous fall, and one multifactorial programme targeting eight specific risk factors. AUTHORS'

conclusionsGroup and home-based exercise programmes, and home safety interventions reduce rate of falls and risk of falling.Multifactorial assessment and intervention programmes reduce rate of falls but not risk of falling; Tai Chi reduces risk of falling.Overall, vitamin D supplementation does not appear to reduce falls but may be effective in people who have lower vitamin D levels before treatment.

Indexed as

Accidental FallsAccidents, HomeAgedBone Density Conservation AgentsEnvironment DesignExerciseFemaleHumansIndependent LivingMalePatient Education as TopicRandomized Controlled Trials as TopicTai JiVitamin DBone Density Conservation AgentsVitamin D

Identifiers

PMID22972103
PMCPMC8095069
OpenAlexW2101076802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 7 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.