ReviewDer Anaesthesist2012
[Cardiopulmonary bypass in cardiac surgery].
Review in Der Anaesthesist, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Clinical risk factors for postoperative infection in adult cardiac surgery with cardiopulmonary bypass: a retrospective study.Infection prevention in practice · 2025Article
- Hepatopathy and acute kidney injury Following Corrective Cardiac Surgery with cardiopulmonary bypass pump in Pediatric with Congenital Heart Defects.ARYA atherosclerosis · 2025Article
- Risk factors and clinical outcome of postoperative hyperglycemia after cardiac surgery with cardiopulmonary bypass.Frontiers in cardiovascular medicine · 2025Article
- Effects of Ozaki procedure on hematological and biochemical parameters.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Article
- Biochemical Changes in Cardiopulmonary Bypass in Cardiac Surgery: New Insights.Journal of personalized medicine · 2023Review
- Article
- Efficacy and safety of inhaled nitric oxide administered during cardiopulmonary bypass for pediatric cardiac surgery: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2023Article
- Management of priming fluids in cardiopulmonary bypass for adult cardiac surgery: network meta-analysis.Annals of medicine · 2023Article
- Ulinastatin in combination with aprotinin improves systemic inflammation in patients undergoing cardiac surgery with cardiopulmonary bypass.American journal of translational research · 2023Article
- Clinical results after hybrid coronary revascularization with totally endoscopic coronary surgery.Journal of cardiothoracic surgery · 2022Observational
- Review
- PaOJournal of thoracic disease · 2020Article
- First experience with Tolvaptan for the treatment of neonates and infants with capillary leak syndrome after cardiac surgery.BMC pediatrics · 2019Article
- Pre-B-cell colony enhancing factor regulates the alveolar epithelial sodium-water transport system through the ERK and AKT pathways.American journal of translational research · 2019Article
- Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats.Molecular medicine reports · 2018Article
- Cardiopulmonary bypass reduces myocardial oxidative stress, inflammation and increases c-kitJournal of translational medicine · 2018Article
- [Perioperative risk and mortality after major surgery].Der Anaesthesist · 2015Review
- Profiling of cell stress protein expression in cardiac tissue of cardiosurgical patients undergoing remote ischemic preconditioning: implications for thioredoxin in cardioprotection.Journal of translational medicine · 2015Article
- Identification of Predictive Early Biomarkers for Sterile-SIRS after Cardiovascular Surgery.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiopulmonary bypass (CPB) is a standard procedure in cardiac surgery; however, apart from its therapeutic options a CPB might also initiate systemic and organ-specific complications, such as heart failure, renal and pulmonary dysfunction, impaired coagulation as well as neurological and cognitive dysfunction. The immunological response to the extracorporeal circulation generates systemic inflammation which often meets the definition of systemic inflammatory response syndrome (SIRS). The main inducers of SIRS are contact of blood with the artificial surfaces of the CPB, mechanical stress which affects the blood components and the extensive surgical trauma. Hence, a number of technical and surgical developments aim at reduction of the inflammatory response caused by the CPB. By reason of surgical demands, the majority of cardiothoracic procedures still depend on the use of CPB; however, there is an on-going development of new techniques trying to reduce the surgical trauma and the negative consequences of CPB. Here, minimized systems with biocompatible surfaces have been shown to be effective in attenuating the inflammatory response to CPB. Alternative procedures such as off-pump surgery may help to avoid CPB-associated complications but due to specific limitations will not replace conventional bypass surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.