Evidence map›Paper›PMID 22971781›Full record

ArticleClinical and vaccine immunology : CVI2012

Western blotting is an efficient tool for differential diagnosis of paracoccidioidomycosis and pulmonary tuberculosis.

Thâmara Aline Bertoni, Maysa Cláudia Zolin Perenha-Viana, Eliana Valéria Patussi, Rosilene Fressatti Cardoso, Terezinha Inez Estivalet Svidzinski

Abstract readEvaluation Study
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Immunologic Diagnosis of Endemic Mycoses.Journal of fungi (Basel, Switzerland) · 2022
    Review
  2. Serological cross-reactivity among common flaviviruses.Frontiers in cellular and infection microbiology · 2022
    Review
  3. Standardization and validation of Dot-ELISA assay forThe journal of venomous animals and toxins including tropical diseases · 2017
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thâmara Aline BertoniLaboratory of Medical Mycology, Department of Clinical Analysis, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Maysa Cláudia Zolin Perenha-Viana
Eliana Valéria Patussi
Rosilene Fressatti Cardoso
Terezinha Inez Estivalet Svidzinski

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sputum and sera from 134 patients screened for tuberculosis (TB) were analyzed to investigate TB and paracoccidioidomycosis (PCM). Of these patients, 11 (8.2%) were confirmed to have TB, but six (4.5%) were positive only for PCM. All patients with PCM presented anti-43-kDa-component antibodies in Western blotting (WB) assays, while in the TB-positive patients these antibodies did not appear. This preliminary study suggests WB as a potential tool for differential laboratory diagnosis between TB and PCM.

Indexed as

AdultAgedAntibodies, FungalBlotting, WesternClinical Laboratory TechniquesDiagnosis, DifferentialDiagnostic Tests, RoutineFemaleHumansMaleMiddle AgedParacoccidioidomycosisSensitivity and SpecificitySerumSputumTuberculosis, PulmonaryAntibodies, Fungal

Identifiers

PMID22971781
PMCPMC3491544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.