Evidence map›Paper›PMID 22971775›Full record

ReviewCellular and molecular life sciences : CMLS2013

Genetic visualization of notch signaling in mammalian neurogenesis.

Itaru Imayoshi, Hiromi Shimojo, Masayuki Sakamoto, Toshiyuki Ohtsuka, Ryoichiro Kageyama

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  5. Article
  6. Astragalus Flavone Induces Proliferation and Differentiation of Neural Stem Cells in a Cerebral Infarction Model.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Genetic Tools to Study Cardiovascular Biology.Frontiers in physiology · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. eLife · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Itaru ImayoshiInstitute for Virus Research, Kyoto University, Shogoin-Kawahara, Sakyo-ku, Kyoto, 606-8507, Japan. iimayosh@virus.kyoto-u.ac.jp
Hiromi Shimojo
Masayuki Sakamoto
Toshiyuki Ohtsuka
Ryoichiro Kageyama

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Notch signaling plays crucial roles in fate determination and the differentiation of neural stem cells in embryonic and adult brains. It is now clear that the notch pathway is under more complex and dynamic regulation than previously thought. To understand the functional details of notch signaling more precisely, it is important to reveal when, where, and how notch signaling is dynamically communicated between cells, for which the visualization of notch signaling is essential. In this review, we introduce recent technical advances in the visualization of notch signaling during neural development and in the adult brain, and we discuss the physiological significance of dynamic regulation of notch signaling.

Indexed as

Animalsbeta-GalactosidaseBrainGene Expression RegulationGreen Fluorescent ProteinsHumansLuciferasesMiceMice, TransgenicModels, BiologicalNeurogenesisReceptors, NotchSignal Transductionbeta-GalactosidaseGreen Fluorescent ProteinsLuciferasesReceptors, Notch

Identifiers

PMID22971775
PMCPMC3663255

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.