Evidence map›Paper›PMID 22971035›Full record

ReviewExpert review of pharmacoeconomics & outcomes research2012

Autism spectrum disorders: a review of measures for clinical, health services and cost-effectiveness applications.

Nalin Payakachat, J Mick Tilford, Erica Kovacs, Karen Kuhlthau

Abstract readReview
In one paragraph

Review in Expert review of pharmacoeconomics & outcomes research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Memantine for autism spectrum disorder.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Pooled it
  4. Trial
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  6. BiSCoT: Behavior-Informed Subgroup-Consistent Connectome Template for Interpretable Brain Network Analysis.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nalin PayakachatDivision of Pharmaceutical Evaluation and Policy, University of Arkansas for Medical Sciences, Little Rock, USA. npayakachat@uams.edu
J Mick Tilford
Erica Kovacs
Karen Kuhlthau

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR029884 · NCRR · UNIV OF ARKANSAS FOR MED SCIS · PI LOWERY, CURTIS L · 2009 to 2011
$11.4M
Measuring quality adjusted life years in children with autism spectrum disordersR01MH089466 · NIMH · UNIV OF ARKANSAS FOR MED SCIS · PI KUHLTHAU, KAREN A, TILFORD, JOHN M · 2009 to 2010
$976k
NCRR NIH HHS 1UL1RR029884NCRR NIH HHS UL1 RR029884NIMH NIH HHS R01 MH089466NIMH NIH HHS R01MH089466
6 · The paper itself

Abstract

Autism spectrum disorders (ASDs) are characterized by impairments in social interaction, communication and behavioral functioning that can affect the health-related quality-of-life outcomes of the affected child and the family. ASDs have increased in prevalence, leading to a demand for improved understanding of the comparative effectiveness of different pharmacologic, behavioral, medical and alternative treatments for children as well as systems for providing services. This review describes outcome instruments that can be used for clinical, health services and cost-effectiveness applications. There is a pressing need to identify the most appropriate instruments for measuring health-related quality-of-life outcomes in this population. Studies evaluating the cost-effectiveness of interventions or treatments for children with ASDs using the cost per quality-adjusted life year metric are lacking. Researchers have the potential to contribute greatly to the field of autism by quantifying outcomes that can inform optimal treatment strategies.

Indexed as

Quality of LifeChildChild Development Disorders, PervasiveComparative Effectiveness ResearchCost-Benefit AnalysisDelivery of Health CareHumansOutcome Assessment, Health Care

Identifiers

PMID22971035
PMCPMC3502071

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.