ArticlePloS one2012
Centromeres cluster de novo at the beginning of meiosis in Brachypodium distachyon.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Establishing of 3D-FISH on frozen section and its applying in chromosome territories analysis in Populus trichocarpa.Plant cell reports · 2024Article
- Cytological analysis of the diploid-like inheritance of newly synthesized allotetraploid wheat.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023Article
- Spatial constraints on chromosomes are instrumental to meiotic pairing.Journal of cell science · 2020Article
- Chromosome-nuclear envelope tethering - a process that orchestrates homologue pairing during plant meiosis?Journal of cell science · 2020Review
- The Cohesin Complex Subunit ZmSMC3 Participates in Meiotic Centromere Pairing in Maize.The Plant cell · 2020Article
- De Novo Centromere Formation and Centromeric Sequence Expansion in Wheat and its Wide Hybrids.PLoS genetics · 2016Article
- Telomere- and Telomerase-Associated Proteins and Their Functions in the Plant Cell.Frontiers in plant science · 2016Review
- Spatial distribution of centromeres and telomeres at interphase varies among Brachypodium species.Journal of experimental botany · 2015Article
- Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation.The Journal of cell biology · 2015Article
- Cytomixis doesn't induce obvious changes in chromatin modifications and programmed cell death in tobacco male meiocytes.Frontiers in plant science · 2015Article
- Article
- Centromere pairing in early meiotic prophase requires active centromeres and precedes installation of the synaptonemal complex in maize.The Plant cell · 2013Article
- Sequence organization and evolutionary dynamics of Brachypodium-specific centromere retrotransposons.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In most eukaryotes that have been studied, the telomeres cluster into a bouquet early in meiosis, and in wheat and its relatives and in Arabidopsis the centromeres pair at the same time. In Arabidopsis, the telomeres do not cluster as a typical telomere bouquet on the nuclear membrane but are associated with the nucleolus both somatically and at the onset of meiosis. We therefore assessed whether Brachypodium distachyon, a monocot species related to cereals and whose genome is approximately twice the size of Arabidopsis thaliana, also exhibited an atypical telomere bouquet and centromere pairing. In order to investigate the occurrence of a bouquet and centromere pairing in B distachyon, we first had to establish protocols for studying meiosis in this species. This enabled us to visualize chromosome behaviour in meiocytes derived from young B distachyon spikelets in three-dimensions by fluorescent in situ hybridization (FISH), and accurately to stage meiosis based on chromatin morphology in relation to spikelet size and the timing of sample collection. Surprisingly, this study revealed that the centromeres clustered as a single site at the same time as the telomeres also formed a bouquet or single cluster.
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