ArticleInternational journal of dentistry2012
Tricho-dento-osseous syndrome: diagnosis and dental management.
Article in International journal of dentistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- Wispy, dystrophic hair in a pediatric patient: Expanding the differential with tricho-dento-osseus syndrome.JAAD case reports · 2025Article
- Prosthetic Oral Rehabilitation with CAD/CAM Suprastructures in Patients with Severe Tissue Deficits: A Case Series.Dentistry journal · 2023Article
- The odontoblastic differentiation of dental mesenchymal stem cells: molecular regulation mechanism and related genetic syndromes.Frontiers in cell and developmental biology · 2023Review
- Case report: Enamel renal syndrome: a case series from sub-Saharan Africa.Frontiers in oral health · 2023Article
- Dental management of tricho-dento-osseous syndrome in adolescent patients: Literature review and case presentation.Dental research journal · 2021Article
- Trichodentoosseous syndrome: a case report and review of literature.BJR case reports · 2019Article
- Novel DLX3 variants in amelogenesis imperfecta with attenuated tricho-dento-osseous syndrome.Oral diseases · 2019Article
- Genome-wide detection of copy number variation in Chinese indigenous sheep using an ovine high-density 600 K SNP array.Scientific reports · 2017Article
- Review
- Transcriptional factor DLX3 promotes the gene expression of enamel matrix proteins during amelogenesis.PloS one · 2015Article
- Hypophosphatemic rickets and its dental significance.Iranian journal of pediatrics · 2013Article
- An unusual case of tricho-dento-osseous syndrome.Dental research journalArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tricho-dento-osseous (TDO) syndrome is a rare, autosomal dominant disorder principally characterised by curly hair at infancy, severe enamel hypomineralization and hypoplasia and taurodontism of teeth, sclerotic bone, and other defects. Diagnostic criteria are based on the generalized enamel defects, severe taurodontism especially of the mandibular first permanent molars, an autosomal dominant mode of inheritance, and at least one of the other features (i.e., nail defects, bone sclerosis, and curly, kinky or wavy hair present at a young age that may straighten out later). Confusion with amelogenesis imperfecta is common; however, taurodontism is not a constant feature of any of the types of amelogenesis imperfecta. Management of TDO requires a team approach, proper documentation, and a long-term treatment and follow-up plan. The aim of treatment is to prevent problems such as sensitivity, caries, dental abscesses, and loss of occlusal vertical dimension through attrition of hypoplastic tooth structure. Another aim is to restore function of the dentition and enhance the esthetics and self-esteem of the patient. This paper proposes treatment approaches that include preventive, restorative, endodontic, prosthetic, and surgical options to management. In addition, it sheds light on the difficulties faced during dental treatment of such cases.
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Registered trials
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