ArticleJournal of Korean medical science2012
Usefulness of glycated hemoglobin as diagnostic criteria for metabolic syndrome.
Article in Journal of Korean medical science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Estimated glucose disposal rate and microvascular complications of diabetes mellitus type I: A systematic review and meta-analysis.Diabetes & vascular disease researchPooled it
- Assessing the reliability and validity for metabolic syndrome diagnosis using point-of-care analyzers in a mobile setup - a pilot study.BMC primary care · 2026Article
- Exposure to per- and polyfluoroalkyl substances and adult cardiometabolic health: a Canadian Health Measures Survey mixture analysis.Environmental health : a global access science source · 2026Article
- Profile and predictors of metabolic syndrome among young adults attending a Medical College in Quetta City, Pakistan.Journal of pharmaceutical policy and practice · 2026Article
- Association between metabolic syndrome and chronic kidney disease in the Brazilian population, a cross-sectional analysis.Scientific reports · 2025Article
- Exploring Socio-Behavioral Correlates of Metabolic and Inflammatory Risk in a University Sample Residing Along the U.S./Mexico Border: A Pilot Study Concomitantly Collecting Survey Data, Blood and Hair Samples, and Physical Measures.International journal of environmental research and public health · 2025Article
- Binge Eating Disorder and Metabolic Syndrome: Shared Mechanisms and Clinical Implications.Healthcare (Basel, Switzerland) · 2025Review
- Serum LEAP2 Levels Across the Spectrum of Metabolic Dysfunction-Associated Fatty Liver Disease: A Potential Noninvasive Biomarker for Severity Stratification.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- The Prevalence of Metabolic Syndrome and Undiagnosed Diabetes in Periodontitis Patients and Non-Periodontitis Controls in a Dental School.Journal of clinical medicine · 2024Article
- Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population.Journal of diabetes and metabolic disorders · 2024Review
- Metabolic Syndrome in Fasting and Non-Fasting Participants: The UAE Healthy Future Study.International journal of environmental research and public health · 2022Article
- Predictive Value of HbA1c and Metabolic Syndrome for Renal Outcome in Non-Diabetic CKD Stage 1-4 Patients.Biomedicines · 2022Article
- "Big Data" Approaches for Prevention of the Metabolic Syndrome.Frontiers in genetics · 2022Review
- The Oral, Gut Microbiota and Cardiometabolic Health of Indigenous Orang Asli Communities.Frontiers in cellular and infection microbiology · 2022Article
- Association between Serum Osteocalcin Levels and Metabolic Syndrome according to the Menopausal Status of Korean Women.Journal of Korean medical science · 2021Article
- Effect of an intensive lifestyle intervention on the prevalence of metabolic syndrome and its components among overweight and obese adults.Journal of public health (Oxford, England) · 2020Article
- Population-derived cut-off for HbA1c could enhance the identification of metabolic syndrome among non-diabetic population.Heliyon · 2020Article
- Metabolic Syndrome Including Glycated Hemoglobin A1c in Adults: Is It Time to Change?Journal of clinical medicine · 2019Article
- Examining the relationship between body mass index and adverse cardio-metabolic profiles among Australian Indigenous and non-Indigenous young adults.Scientific reports · 2019Article
- Comparative Abilities of Fasting Plasma Glucose and Haemoglobin A1c in Predicting Metabolic Syndrome among Apparently Healthy Normoglycemic Ghanaian Adults.International journal of chronic diseases · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The metabolic syndrome (MetS) is the clustering of cardiovascular risk factors and known as a powerful predictor of diabetes and cardiovascular disease. Glycated hemoglobin (HbA1c) is used as one of the diagnostic criteria for diabetes and category of increased risk for diabetes. We examined the usefulness of HbA1c as a diagnostic tool for MetS and to determine the cut-off value of HbA1c as a criterion for MetS, in non-diabetic Korean subjects. We analyzed 7,307 participants (male: 4,181, 57%) in a medical check-up program, and applied the newly recommended guidelines of the International Diabetes Federation for diagnosis of MetS. The mean HbA1c was 5.54% in all subjects and showed no significant difference between genders. Using receiver-operating characteristic curve, HbA1c value corresponding to the fasting plasma glucose value of 100 mg/dL was 5.65% (sensitivity 52.3%, specificity 76.7%). The prevalence of MetS was 8.5% according to the IDF guideline and 10.9% according to HbA1c value of 5.7%, showing 69.5% agreement rate. The detection rate of MetS increased to 25.7% using the HbA1c criterion of 5.7% instead of fasting hyperglycemia. This study suggests that HbA1c might be used as a diagnostic criterion for MetS and the appropriate cut-off value of HbA1c may be 5.65% in this Korean population.
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