Evidence map›Paper›PMID 22969217›Full record

ArticleWorld journal of gastroenterology2012

Diagnostic criteria for autoimmune hepatitis in children: a challenge for pediatric hepatologists.

Priscila Menezes Ferri, Alexandre Rodrigues Ferreira, Débora Marques Miranda, Ana Cristina Simões E Silva

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Pathogenesis of Autoimmune Hepatitis-Cellular and Molecular Mechanisms.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Article
  8. A 6-year-old boy with Wilson disease-A diagnostic dilemma.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Kupffer Cell Hyaline Globules in Children With Autoimmune Hepatitis.Journal of clinical and experimental hepatology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Priscila Menezes FerriDivision of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, School Medicine, Federal University of Minas Gerais, Minas Gerais 30130-100, Brazil.
Alexandre Rodrigues Ferreira
Débora Marques Miranda
Ana Cristina Simões E Silva

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder that is rare in children and adolescents. AIH has a broad clinical spectrum and a quick response to treatment with corticosteroids and immunosuppressive medication. The available diagnosis criteria have limitations and should be evaluated in pediatric populations. Recently, some studies reported that the 2008 simplified diagnostic criteria for AIH could be used in children with high sensibility and specificity. In addition, the authors reported that globulin and immunoglobulin G levels can be used interchangeably for diagnostic purposes. They also demonstrated that the 2008 simplified criteria fail in identifying patients with fulminant hepatic failure. Here, we discuss the limitations of the use of these criteria in pediatric patients and the requirement of more studies to improve the diagnosis of AIH in children.

Indexed as

Autoimmune hepatitisAutoimmunityChildDiagnosisLiver diseases

Identifiers

PMID22969217
PMCPMC3435769

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.