ArticleWorld journal of gastroenterology2012
Significant decrease in prevalence of Helicobacter pylori in the Czech Republic.
Article in World journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Prevalence of Helicobacter pylori infection worldwide: a systematic review of studies with national coverage.Digestive diseases and sciences · 2014Pooled it
- Prevalence of Helicobacter Pylori in Obese Adults: A Literature Review.Physiological research · 2025Review
- The Aging Stomach: Clinical Implications ofInternational journal of molecular sciences · 2024Review
- Review of foodborne helicobacteriosis.Italian journal of food safety · 2024Review
- Low Prevalence of HSV-1 andDiagnostics (Basel, Switzerland) · 2023Article
- Focusing onFrontiers in cellular and infection microbiology · 2023Review
- Worldwide Prevalence and Risk Factors ofChildren (Basel, Switzerland) · 2022Review
- Advances in the Aetiology & Endoscopic Detection and Management of Early Gastric Cancer.Cancers · 2021Review
- The Prevalence ofJournal of clinical medicine research · 2020Article
- Molecular Phylogenetic Analysis ofInternational journal of microbiology · 2020Article
- Epidemiologic characteristics ofWorld journal of gastroenterology · 2019Observational
- Helicobacter pylori infection in children: an overview of diagnostic methods.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Review
- Gastric cancer and family history.The Korean journal of internal medicine · 2016Review
- Helicobacter pylori status among patients undergoing gastroscopy in rural northern Alberta.Canadian family physician Medecin de famille canadien · 2016Article
- Atrophic gastritis and enlarged gastric folds diagnosed by double-contrast upper gastrointestinal barium X-ray radiography are useful to predict future gastric cancer development based on the 3-year prospective observation.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2016Observational
- Prevention of Helicobacter pylori infection in childhood.World journal of gastroenterology · 2014Review
- Helicobacter pylori infection in older people.World journal of gastroenterology · 2014Review
- Blood pressure and stature in Helicobacter pylori positive and negative persons.World journal of gastroenterology · 2014Article
- Article
- How antibiotic resistances could change Helicobacter pylori treatment: A matter of geography?World journal of gastroenterology · 2013Review
Corrections and comments
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Authors and funding
11 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study possible decrease in prevalence of Helicobacter pylori (H. pylori) infection in the Czech Republic within a 10-year period.
methodsA total of 22 centres entered the study. The catchment areas of these centres covered cities and towns with more than 20,000 inhabitants, smaller towns (≤ 20,000 inhabitants) with surrounding villages and rural areas, and were spread over the whole country, corresponding well to the geographical distribution of the Czech population. A total of 1,837 subjects (aged 5-98 years) took part in the study, randomly selected out of 38,147 people from the general population. H. pylori infection was investigated by means of a (13)C-urea breath test. Breath samples in duplicates were analysed using isotope ratio mass spectrometry. The cut-off point was 3.5. Social and demographic characteristics were based on data from self-completed questionnaires.
resultsThe overall prevalence of H. pylori infection was 23.5% (430/1826), and 4.8% (20/420) in children aged 15 or less. There was no statistically significant difference in prevalence between males (24.3%; 208/857) and females (22.9%, 222/969, P = 0.494). H. pylori infection was strongly associated with higher age, among subjects aged 55+ years, prevalence of H. pylori infection was 39.8% (252/633, P < 0.001). The highest prevalence of H. pylori infection was found among persons aged 55-64 years (43.9%, 97/221) and 75+ years (37.9%, 58/153). Among study subjects aged 15+ years, prevalence of H. pylori infection was significantly increased in those with lowest education (odds risk 3.19, 95% CI 1.87-5.47). Compared to never married (14.1%), the prevalence of H. pylori infection was statistically significantly higher among married (35.4%, 246/694, P < 0.001), divorced (36.8%, 49/133, P < 0.001) and widowed study subjects (40.2%, 45/112, P < 0.001), both in minimally and fully adjusted analysis. There was no significant difference in the prevalence of H. pylori infection between married and widowed subjects (35.4%, 246/694 vs 40.2%, 45/112, P = 0.389). There was little variation in smoking prevalence across categories of smoking and there was no evidence of an increased risk of H. pylori infection among current or past smokers in our data (odds risk 1.04 with 95% CI 0.78-1.40 for current smokers; odds ratio 0.83 with 95% CI 0.60-1.16 for former smokers). The current prevalence of H. pylori in 2011 was significantly lower compared to the prevalence reported from identical geographical areas in 2001 (23.5% vs 41.7%, P < 0.001).
conclusionThe overall prevalence of H. pylori infection in the general population has fallen substantially in the Czech Republic over the past 10 years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.