ArticleZoo biology
Hypertension increases with aging and obesity in chimpanzees (Pan troglodytes).
Article in Zoo biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 46 citations in OpenAlex.
- Global Data From Great Ape Zoo Populations Confirm a High Prevalence of Overweight Individuals.American journal of primatology · 2026Article
- Multimorbidity and animal models.Animal models and experimental medicine · 2025Review
- Usefulness of noninvasive blood pressure measurement in captive Red Panda (Ailurus fulgens).The Journal of veterinary medical science · 2024Article
- Age-related physiological dysregulation progresses slowly in semi-free-ranging chimpanzees.Evolution, medicine, and public health · 2024Article
- Body mass and growth rates in captive chimpanzees (Pan troglodytes) cared for in African wildlife sanctuaries, zoological institutions, and research facilities.Zoo biology · 2023Article
- Evolutionary Approaches in Aging Research.Cold Spring Harbor perspectives in medicine · 2022Review
- Age-associated epigenetic change in chimpanzees and humans.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Validation and utility of a body condition scoring system for chimpanzees (Pan troglodytes).American journal of primatology · 2020Article
- Large Lemurs: Ecological, Demographic and Environmental Risk Factors for Weight Gain in Captivity.Animals : an open access journal from MDPI · 2020Article
- The implementation and initial evaluation of a physical therapy program for captive chimpanzees (Pan troglodytes).American journal of primatology · 2020Article
- Neutrophil to Lymphocyte Ratio (NLR) in captive chimpanzees (Pan troglodytes): The effects of sex, age, and rearing.PloS one · 2020Article
- Differences in Behavior Between Elderly and Nonelderly Captive Chimpanzees and the Effects of the Social Environment.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- Aging research using the common marmoset: Focus on aging interventions.Nutrition and healthy aging · 2019Article
- Non-human primates as a model for aging.Biochimica et biophysica acta. Molecular basis of disease · 2018Review
- Distinguishing between determinate and indeterminate growth in a long-lived mammal.BMC evolutionary biology · 2015Article
- The influence of body mass index, age and sex on inflammatory disease risk in semi-captive Chimpanzees.PloS one · 2014Article
- Larger Than Life? Body Mass Records of Zoo-Managed Giant Anteaters (Myrmecophaga tridactyla).Zoo biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cardiovascular disease is a primary cause of morbidity and mortality in captive chimpanzees. Four years of blood pressure (BP) data were analyzed from a captive former laboratory population of 201 healthy adult chimpanzees with assessment of age and obesity on elevated BP. Five different measures of obesity were compared: abdominal girth, basal metabolic rate, body-mass index (BMI), body weight, and surface area. Systolic BP varied by sex. Obesity did not influence male BP. For females, obesity was a significant determinant of BP. The best measure of female obesity was basal metabolic rate and the worst was BMI. Median systolic BP of healthy weight females (<54.5 kg) was significantly lower (128 mmHg) than overweight or obese females (140 mmHg), but both were lower than all males (147 mmHg). For diastolic BP, neither sex nor any of the five obesity measures was significant. But age was highly significant, with geriatric chimpanzees (>30 years) having higher median diastolic BP (74 mmHg) than young adults of 10-29 years of age (65 mmHg). By these criteria, 80% of this population is normotensive, 7% prehypertensive, and 13% hypertensive. In summary, systolic BP intervals required adjustment for obesity among females but not males. Diastolic BP required adjustment for advanced age (≥30 years). Use of these reference intervals can facilitate timely clinical care of captive chimpanzees.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.