ArticleBritish journal of cancer2012
Case-control study of paternal occupation and childhood leukaemia in Great Britain, 1962-2006.
Article in British journal of cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Parental occupational paint exposure and risk of childhood leukemia in the offspring: findings from the Childhood Leukemia International Consortium.Cancer causes & control : CCC · 2014Pooled it
- Residential proximity to agriculture and risk of childhood leukemia and central nervous system tumors in the Danish national birth cohort.Environment international · 2020Article
- Occupational livestock or animal dust exposure and offspring cancer risk in Denmark, 1968-2016.International archives of occupational and environmental health · 2020Article
- Parental occupational organic dust exposure and selected childhood cancers in Denmark 1968-2016.Cancer epidemiology · 2020Article
- Case-control study of paternal occupational exposures and childhood bone tumours and soft-tissue sarcomas in Great Britain, 1962-2010.British journal of cancer · 2020Article
- Parental occupational exposure to pesticides, animals and organic dust and risk of childhood leukemia and central nervous system tumors: Findings from the International Childhood Cancer Cohort Consortium (I4C).International journal of cancer · 2020Article
- Parental occupational exposure to diesel engine exhaust in relation to childhood leukaemia and central nervous system cancers: a register-based nested case-control study in Denmark 1968-2016.Occupational and environmental medicine · 2019Article
- Case-control study of paternal occupational exposures and childhood lymphoma in Great Britain, 1962-2010.British journal of cancer · 2019Article
- Alterations of Hematologic and Hematopoietic Parameters in Mice Exposed to Pulsed Electromagnetic Field.Journal of immunology research · 2019Article
- Childhood cancer research in Oxford II: The Childhood Cancer Research Group.British journal of cancer · 2018Article
- Livestock and poultry density and childhood cancer incidence in nine states in the USA.Environmental research · 2017Article
- A task-based assessment of parental occupational exposure to organic solvents and other compounds and the risk of childhood leukemia in California.Environmental research · 2016Article
- A case-control study of occupational contact levels in the childhood leukaemia cluster at Seascale, Cumbria, UK.BMJ open · 2015Article
- Parental occupational pesticide exposure and the risk of childhood leukemia in the offspring: findings from the childhood leukemia international consortium.International journal of cancer · 2014Article
- Residential distance at birth from overhead high-voltage powerlines: childhood cancer risk in Britain 1962-2008.British journal of cancer · 2014Article
- Leukaemia in young children in the vicinity of British nuclear power plants: a case-control study.British journal of cancer · 2013Article
- The Childhood Leukemia International Consortium.Cancer epidemiology · 2013Article
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9 authors.
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Abstract
backgroundPaternal occupational exposures have been proposed as a risk factor for childhood leukaemia. This study investigates possible associations between paternal occupational exposure and childhood leukaemia in Great Britain.
methodsThe National Registry of Childhood Tumours provided all cases of childhood leukaemia born and diagnosed in Great Britain between 1962 and 2006. Controls were matched on sex, period of birth and birth registration subdistrict. Fathers' occupations were assigned to 1 or more of 33 exposure groups. Social class was derived from father's occupation at the time of the child's birth.
resultsA total of 16 764 cases of childhood leukaemia were ascertained. One exposure group, paternal social contact, was associated with total childhood leukaemia (odds ratio 1.14, 1.05-1.23); this association remained significant when adjusted for social class. The subtypes lymphoid leukaemia (LL) and acute myeloid leukaemia showed increased risk with paternal exposure to social contact before adjustment for social class. Risk of other leukaemias was significantly increased by exposure to electromagnetic fields, persisting after adjustment for social class. For total leukaemia, the risks for exposure to lead and exhaust fumes were significantly <1. Occupationally derived social class was associated with risk of LL, with the risk being increased in the higher social classes.
conclusionOur results showed some support for a positive association between childhood leukaemia risk and paternal occupation involving social contact. Additionally, LL risk increased with higher paternal occupational social class.
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