Evidence map›Paper›PMID 22968448›Full record

ArticleLifetime data analysis2013

Competing risks with missing covariates: effect of haplotypematch on hematopoietic cell transplant patients.

Thomas H Scheike, Martin J Maiers, Vanderson Rocha, Mei-Jie Zhang

Abstract read
In one paragraph

Article in Lifetime data analysis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Risk factors of CVD mortality among the elderly in Beijing, 1992 - 2009: an 18-year cohort study.International journal of environmental research and public health · 2014
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas H ScheikeDepartment of Biostatistics, University of Copenhagen, Copenhagen, Denmark. ts@biostat.ku.dk
Martin J Maiers
Vanderson Rocha
Mei-Jie Zhang

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
TECHNIQUES FOR MODELING COMPLEX LONGITUDINAL STUDIESR01CA054706 · NCI · OHIO STATE UNIVERSITY · PI KLEIN, JOHN P. · 1991 to 2010
$2.0M
NCI NIH HHS 2 R01 CA54706-10NCI NIH HHS R01 CA054706NCI NIH HHS U24 CA076518
6 · The paper itself

Abstract

In this paper we consider a problem from hematopoietic cell transplant (HCT) studies where there is interest on assessing the effect of haplotype match for donor and patient on the cumulative incidence function for a right censored competing risks data. For the HCT study, donor's and patient's genotype are fully observed and matched but their haplotypes are missing. In this paper we describe how to deal with missing covariates of each individual for competing risks data. We suggest a procedure for estimating the cumulative incidence functions for a flexible class of regression models when there are missing data, and establish the large sample properties. Small sample properties are investigated using simulations in a setting that mimics the motivating haplotype matching problem. The proposed approach is then applied to the HCT study.

Indexed as

HaplotypesGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHistocompatibility TestingHLA AntigensHumansLife TablesModels, StatisticalProportional Hazards ModelsRegression AnalysisRisk FactorsHLA Antigens

Identifiers

PMID22968448
PMCPMC3817559

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.