Evidence map›Paper›PMID 22968160›Full record

ReviewTherapeutic advances in respiratory disease2012

Fluoroquinolones in the treatment of bronchopulmonary disease in cystic fibrosis.

Matthew Hurley, Alan Smyth

Open access · greenAbstract readReview
In one paragraph

Review in Therapeutic advances in respiratory disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Matthew HurleyDivision of Child Health, University of Nottingham, Queens Medical Centre, Nottingham, UK. matthew.hurley@nottingham.ac.uk
Alan Smyth
Queen's Medical Centre · GBUniversity of Nottingham · GB

Funding

Wellcome Trust 092295Wellcome Trust WT092295MA
6 · The paper itself

Abstract

Fluoroquinolones are commonly used to treat lung infections in patients with cystic fibrosis. These patients are susceptible to lung infection with common bacteria such as Staphylococcus aureus and Haemophilus influenzae, but are also prone to infection by opportunistic bacteria, including Pseudomonas aeruginosa. The good oral bioavailability and broad antimicrobial spectrum of activity, including antipseudomonal properties, make this class of antimicrobial attractive. We review the evidence assessing the use of fluoroquinolones in the context of preventing and eradicating early lung infection and in managing chronic lung infection and pulmonary exacerbations. The safety of fluoroquinolones and the use of newer agents in the class are also discussed.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsBiological AvailabilityCystic FibrosisFluoroquinolonesHumansLung DiseasesPseudomonas aeruginosaPseudomonas InfectionsAnti-Bacterial AgentsFluoroquinolones

Identifiers

PMID22968160
PMCPMC3509170
OpenAlexW2154651294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.