Evidence map›Paper›PMID 22967207›Full record

ArticleFEMS microbiology letters2012

A novel gene, ardD, determines antirestriction activity of the non-conjugative transposon Tn5053 and is located antisense within the tniA gene.

Vladimir P Balabanov, Vera Yu Kotova, Gennady Y Kholodii, Sofia Z Mindlin, Gennadii B Zavilgelsky

Abstract read
In one paragraph

Article in FEMS microbiology letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Spread of Antibiotic Resistance Genes In Vivo Model.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Anti-Restriction Protein, KlcAFrontiers in cellular and infection microbiology · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vladimir P BalabanovState Research Institute of Genetics and Selection of Industrial Microorganisms (GosNIIgenetika), Moscow, Russia.
Vera Yu Kotova
Gennady Y Kholodii
Sofia Z Mindlin
Gennadii B Zavilgelsky

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mercury-resistance transposon Tn5053 inhibits restriction activity of the type I restriction-modification endonuclease EcoKI in Escherichia coli K12 cells. This is the first report of antirestriction activity of a non-conjugative transposon. The gene (ardD) coding for the antirestriction protein has been cloned. The ardD gene is located within the tniA gene, coding for transposase, on the complementary strand. The direction of transcription is opposite to transcription of the tniA gene.

Indexed as

DNA Transposable ElementsGene Expression Regulation, BacterialCloning, MolecularDNA Restriction EnzymesEscherichia coli K12Escherichia coli ProteinsTranscription, GeneticTransposasesardD protein, E coliDNA Restriction EnzymesDNA Transposable Elementsendodeoxyribonuclease EcoKIEscherichia coli ProteinsTniA transposaseTransposases

Identifiers

PMID22967207
PMCPMC3533173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.