Evidence map›Paper›PMID 22966898›Full record

ArticleAIDS research and human retroviruses2012

Biology of mucosally transmitted sexual infection-translating the basic science into novel HIV intervention: a workshop summary.

Damian Purcell, Anthony Cunningham, Stuart Turville, Gilda Tachedjian, Alan Landay

Abstract readConference Proceedings
In one paragraph

Article in AIDS research and human retroviruses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Improving Adherence to Post-Cervical Biopsy Sexual Abstinence in Kenyan Female Sex Workers.American journal of reproductive immunology (New York, N.Y. : 1989) · 2016
    Trial
  2. Cell-to-Cell Spread of HIV and Viral Pathogenesis.Advances in virus research · 2016
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Damian PurcellUniversity of Melbourne, Parkville, Australia.
Anthony Cunningham
Stuart Turville
Gilda Tachedjian
Alan Landay

Funding

Tissue Culture and Virology Laboratory CoreP01AI082971 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI LANDAY, ALAN L · 2009 to 2013
$11.2M
DevelopmentalP30AI082151 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI LANDAY, ALAN L · 2009 to 2014
$4.6M
NIAID NIH HHS P01 AI 082971-04NIAID NIH HHS P30 AI 082151-04
6 · The paper itself

Abstract

A group of over 200 international scientists came together on April 15 in Sydney, Australia just before the 2012 International Microbicides Conference as a part of a workshop to address the basic concepts and factors that modulate HIV infection at the mucosal surface. The meeting focused on defining the interaction between virus, prevailing host physiology, microbiota, and innate and adaptive immune responses and how they combine to impact the outcome at the moment of potential viral transmission. Speakers examined the biology of HIV entry during transmission, innate and natural antiviral mechanisms at the mucosa, microbicide efficacy, pharmacokinetic, and pharmacodynamics, animal models, and opportunities for combining HIV prevention strategies. Other viral infection models both in vivo and in vitro were considered for the insights they provided into HIV transmission events. The workshop raised important questions that we need to answer to further our basic understanding of host and viral factors influencing HIV transmission to inform the development of novel prevention strategies.

Indexed as

Adaptive ImmunityImmunity, InnateAIDS VaccinesAnimalsAnti-Infective AgentsAustraliaFemaleHIV InfectionsHost-Pathogen InteractionsHumansMaleModels, AnimalMucous MembraneSexual BehaviorAIDS VaccinesAnti-Infective Agents

Identifiers

PMID22966898
PMCPMC3484787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.