Evidence map›Paper›PMID 22966873›Full record

ArticleOrganic letters2012

Synthesis of the reported structures for kealiinines B and C.

Joseph B Gibbons, Keith M Gligorich, Bryan E Welm, Ryan E Looper

Abstract read
In one paragraph

Article in Organic letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Novel (2-amino-4-arylimidazolyl)propanoic acids and pyrrolo[1,2-Beilstein journal of organic chemistry · 2019
    Article
  4. Article
  5. Article
  6. Total synthesis and cytotoxicity of Leucetta alkaloids.Bioorganic & medicinal chemistry · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Studies Towards theEuropean journal of organic chemistry · 2015
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph B GibbonsDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, USA.
Keith M Gligorich
Bryan E Welm
Ryan E Looper

Funding

Synthetic and biological investigations of 2-aminoimidazole derived natural products.R01GM090082 · NIGMS · UNIVERSITY OF UTAH · PI LOOPER, RYAN EDWARD · 2010 to 2019
$2.6M
Identification of Novel Cancer Selective Compounds in 3D Tumor Organoid AssaysR01CA140296 · NCI · UNIVERSITY OF UTAH · PI SIGMAN, MATTHEW S · 2009 to 2013
$1.5M
NCI NIH HHS R01 CA140296NCI NIH HHS R01-CA140296NIGMS NIH HHS R01 GM090082NIGMS NIH HHS R01-GM090082
6 · The paper itself

Abstract

Syntheses of the reported structures of kealiinines B and C have been executed. An intermolecular electrophile-induced cyclization of a pendant arene on an ene-guanidine affords the tetracyclic, oxidized naphthimidazole cores.

Indexed as

AlkaloidsCyclizationGuanidineMolecular StructureOxidation-ReductionStereoisomerismAlkaloidsGuanidinekealiinine Bkealiinine C

Identifiers

PMID22966873
PMCPMC3619427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.