Evidence map›Paper›PMID 22965809›Full record

ArticleThe Laryngoscope2013

Mechanical analysis of cartilage graft reinforced with PDS plate.

Christian Conderman, Michael Kinzinger, Cyrus Manuel, Dmitry Protsenko, Brian J F Wong

Abstract read
In one paragraph

Article in The Laryngoscope, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christian CondermanDepartment of Otolaryngology-Head &Neck Surgery, University of California-Irvine, Medical Center, Irvine, California 92617, USA.
Michael Kinzinger
Cyrus Manuel
Dmitry Protsenko
Brian J F Wong
Case Western Reserve University · US

Funding

Electromechanical reshaping of tissueR21DE019026 · NIDCR · UNIVERSITY OF CALIFORNIA-IRVINE · PI WONG, BRIAN · 2009 to 2010
$419k
NIDCR NIH HHS R21 DE019026
6 · The paper itself

Abstract

objectives/hypothesisThis study attempts to characterize the biomechanical properties of a PDS-cartilage composite graft for use in septorhinoplasty. STUDY

designExperimental Study.

methodsThis study used a PDS analog, porcine cartilage cut to 1 × 5 × 20 mm, and a mechanical testing platform to measure flexure of a composite graft. Samples were assessed in four groups based on variations in suture pattern and orientation. The platform measured the force required to deflect the sample 2 mm in single cantilever beam geometry before and after the polymer was affixed to the specimen. Elastic Moduli were calculated before and after application of the polydioxanone polymer.

resultsThe average modulus of the cartilage alone was 17 ± 0.9 MPa. The modulus of the composite cartilage-polymer graft with 2 suture fixation was 21.2 ± 1.5 MPa. The 3-suture configuration produced an increase to 25.8 ± 2.23 MPa. The four-suture configuration produced 23.1 ± 3.19 MPa. The five-suture configuration produced 25.7 ± 2.6 MPa. The modulus of the analog alone was 170 ± 30 MPa. The modulus of the 0.5 mm PDS was 692 ± 37.4 MPa. The modulus of the 0.15 mm perforated PDS was 447 ± 34.8 MPa.

conclusionsThe study found that suturing a polymer plate to cartilage resulted in enhanced stiffness of the composite. Under the conditions of the study, there was no significant difference in elastic moduli between suture configurations, making the two-suture linear configuration optimal in the one-plane cantilever deflection model.

Indexed as

Analysis of VarianceAnimalsBiomechanical PhenomenaCartilageElastic ModulusMaterials TestingNasal CartilagesPolydioxanoneRibsStress, MechanicalSuture TechniquesSwinePolydioxanone

Identifiers

PMID22965809
PMCPMC4127303
OpenAlexW2061698093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.