Evidence map›Paper›PMID 22965650›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2013

Prior fundoplication does not improve safety or efficacy outcomes of radiofrequency ablation: results from the U.S. RFA Registry.

Nicholas J Shaheen, Hannah P Kim, William J Bulsiewicz, William D Lyday, George Triadafilopoulos, Herbert C Wolfsen, Srinadh Komanduri, Gary W Chmielewski, Atilla Ertan, F Scott Corbett and 3 more

Registry-linked trialAbstract readComparative StudyEvaluation StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00848237 (HALO Patient Registry), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00848237 nacompletednot on this map

HALO Patient Registry: Ablation of Barrett's Esophagus, A Multi-Center Patient Registry

TypeinterventionalSponsorMedtronic - MITGRan2007 to 2014Enrolled5,521ConditionsBarrett EsophagusArmsRadiofrequency Ablation (HALO Ablation Systems)
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Advances in the Diagnosis and Treatment of Barrett's Esophagus and Early Esophageal Cancer; Summary of the Kelly and Carlos Pellegrini SSAT/SAGES Luncheon Symposium.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Review
  6. Observational
  7. Article
  8. Observational
  9. Article
  10. Observational
  11. The Durability of Endoscopic Therapy for Treatment of Barrett's Metaplasia, Dysplasia, and Mucosal Cancer After Nissen Fundoplication.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
    Article
  12. Review
  13. Durability and predictors of successful radiofrequency ablation for Barrett's esophagus.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2014
    Article
  14. Volume-outcome associations after major hepatectomy for hepatocellular carcinoma: a nationwide Taiwan study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2014
    Article
  15. Review
  16. Review
  17. Update on ablation for Barrett's esophagus.Current gastroenterology reports · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Nicholas J ShaheenUniversity of North Carolina School of Medicine, 130 Mason Farm Rd, CB#7080, Chapel Hill, NC 27599-7080, USA. nicholas_shaheen@med.unc.edu
Hannah P Kim
William J Bulsiewicz
William D Lyday
George Triadafilopoulos
Herbert C Wolfsen
Srinadh Komanduri
Gary W Chmielewski
Atilla Ertan
F Scott Corbett
Daniel S Camara
Richard I Rothstein
Bergein F Overholt
University of North Carolina at Chapel Hill · USAtlanta Gastroenterology Associates · USBeaumont Hospital, Troy · USDartmouth College · USDigestive Care (United States) · USJacksonville College · USNorthwestern University · USPalo Alto University · USSarasota University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOngoing gastroesophageal reflux may impair healing and re-epithelialization after radiofrequency ablation (RFA) of Barrett's esophagus (BE). Because prior fundoplication may improve reflux control, our aim was to assess the relationship between prior fundoplication and the safety/efficacy of RFA.

methodsWe assessed the U.S. RFA Registry, a nationwide registry of BE patients receiving RFA at 148 institutions, to compare the safety and efficacy of ablation between those with prior fundoplication and those with medical management (proton pump inhibition).

resultsAmong 5,537 patients receiving RFA, 301 (5.4 %) had prior fundoplication. Of fundoplication subjects, 1.0 % developed stricture and 1.0 % were hospitalized after RFA. Rates of stricture, bleeding, and hospitalization were not statistically different (p = ns) between patients with and without prior fundoplication. Complete eradication of intestinal metaplasia and complete eradication of dysplasia were achieved in 71 % and 87 % of fundoplication patients, and 73 % and 87 % of patients without fundoplication, respectively (p = ns for both). Patients with prior fundoplication needed similar numbers of RFA sessions for eradication compared with those without fundoplication.

conclusionsRadiofrequency ablation, with or without prior fundoplication, is safe and effective in eradicating BE. Prior fundoplication was associated with similar adverse event and efficacy rates when compared with medical management.

Indexed as

Catheter AblationFundoplicationAgedBarrett EsophagusFemaleFollow-Up StudiesGastroesophageal RefluxHospitalizationHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesProton Pump InhibitorsRegistriesRetrospective StudiesProton Pump Inhibitors

Identifiers

PMID22965650
OpenAlexW2052085161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.