Evidence map›Paper›PMID 22965430›Full record

ReviewNature reviews. Gastroenterology & hepatology2013

Refractory inflammatory bowel disease-could it be an irritable bowel?

Jie Meng, Anurag Agrawal, Peter J Whorwell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Diagnosis and management of functional symptoms in inflammatory bowel disease in remission.World journal of gastrointestinal pharmacology and therapeutics · 2016
    Review
  4. Inflammatory bowel diseases: Current problems and future tasks.World journal of gastrointestinal pharmacology and therapeutics · 2014
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jie MengDepartment of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, 100078 China.
Anurag Agrawal
Peter J Whorwell

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with IBD who are apparently in remission-as indicated by normal blood tests, endoscopic findings and ultrasonography results-often continue to experience symptoms. Furthermore, despite these negative findings, there is a temptation to increase their anti-inflammatory medication in the hope that this approach would lead to some improvement. However, this strategy often seems to fail and can sometimes lead to adverse events. Consequently, when evidence of continuing inflammatory activity is lacking it might be appropriate to consider the possibility of co-existent IBS in these patients and to treat them for this condition. Dietary manipulation, antispasmodic agents, antidepressants (especially of the tricyclic variety) and even behavioural treatments might result in a worthwhile improvement of symptoms.

Indexed as

Anti-Inflammatory AgentsBehavior TherapyComorbidityDiagnosis, DifferentialDisease ManagementHumansInflammatory Bowel DiseasesIrritable Bowel SyndromeAnti-Inflammatory Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.