ArticleMolecular biotechnology2013
Overexpression of alternative oxidase gene confers aluminum tolerance by altering the respiratory capacity and the response to oxidative stress in tobacco cells.
Article in Molecular biotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 66 citations in OpenAlex.
- Article
- Genome-Wide Identification and Characterization ofPlants (Basel, Switzerland) · 2024Article
- 24-Epibrassinolide Reduces Drought-Induced Oxidative Stress by Modulating the Antioxidant System and Respiration in Wheat Seedlings.Plants (Basel, Switzerland) · 2024Article
- The formate dehydrogenase enhances aluminum tolerance of tobacco.Journal of genetics · 2023Article
- Maize (Zea mays L.) responses to salt stress in terms of root anatomy, respiration and antioxidative enzyme activity.BMC plant biology · 2022Article
- Altering the balance between AOX1A and NDB2 expression affects a common set of transcripts in Arabidopsis.Frontiers in plant science · 2022Article
- Overexpression of the Aldehyde Dehydrogenase GeneInternational journal of molecular sciences · 2022Article
- Physiological, Biochemical, and Transcriptomic Responses ofInternational journal of molecular sciences · 2020Article
- A MaizeFrontiers in plant science · 2020Article
- Photorespiration is complemented by cyclic electron flow and the alternative oxidase pathway to optimize photosynthesis and protect against abiotic stress.Photosynthesis research · 2019Review
- Hydrogen Peroxide and Nitric Oxide Crosstalk Mediates Brassinosteroids Induced Cold Stress Tolerance inInternational journal of molecular sciences · 2019Article
- Aluminum Responsive Genes in Flax (BioMed research international · 2019Article
- Comparative transcriptome and translatome analysis in contrasting rice genotypes reveals differential mRNA translation in salt-tolerant Pokkali under salt stress.BMC genomics · 2018Article
- Mitochondrial alternative oxidase-dependent autophagy involved in ethylene-mediated drought tolerance in Solanum lycopersicum.Plant biotechnology journal · 2018Article
- Alternative oxidase (AOX) over-expression improves cell expansion and elongation in cotton seedling exposed to cool temperatures.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Tapetal-Delayed Programmed Cell Death (PCD) and Oxidative Stress-Induced Male Sterility ofInternational journal of molecular sciences · 2018Article
- Understanding brassinosteroid-regulated mechanisms to improve stress tolerance in plants: a critical review.Environmental science and pollution research international · 2017Review
- Aluminum, a Friend or Foe of Higher Plants in Acid Soils.Frontiers in plant science · 2017Review
- Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.Frontiers in plant science · 2017Review
- A Formate Dehydrogenase Confers Tolerance to Aluminum and Low pH.Plant physiology · 2016Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aluminum (Al) stress represses mitochondrial respiration and produces reactive oxygen species (ROS) in plants. Mitochondrial alternative oxidase (AOX) uncouples respiration from mitochondrial ATP production and may improve plant performance under Al stress by preventing excess accumulation of ROS. We tested respiratory changes and ROS production in isolated mitochondria and whole cell of tobacco (SL, ALT 301) under Al stress. Higher capacities of AOX pathways relative to cytochrome pathways were observed in both isolated mitochondria and whole cells of ALT301 under Al stress. AOX1 when studied showed higher AOX1 expression in ALT 301 than SL cells under stress. In order to study the function of tobacco AOX gene under Al stress, we produced transformed tobacco cell lines by introducing NtAOX1 expressed under the control of the cauliflower mosaic virus (CaMV) 35 S promoter in sensitive (SL) Nicotiana tabacum L. cell lines. The enhancement of endogenous AOX1 expression and AOX protein with or without Al stress was in the order of transformed tobacco cell lines > ALT301 > wild type (SL). A decreased respiratory inhibition and reduced ROS production with a better growth capability were the significant features that characterized AOX1 transformed cell lines under Al stress. These results demonstrated that AOX plays a critical role in Al stress tolerance with an enhanced respiratory capacity, reducing mitochondrial oxidative stress burden and improving the growth capability in tobacco cells.
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