ReviewInternational journal of clinical pharmacy2012
Prevalence of drug interactions in hospital healthcare.
Review in International journal of clinical pharmacy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 7 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Heterogeneity in the Identification of Potential Drug-Drug Interactions in the Intensive Care Unit: A Systematic Review, Critical Appraisal, and Reporting Recommendations.Journal of clinical pharmacology · 2022Pooled it
- Prevalence of drug interactions in hospitalised elderly patients: a systematic review.European journal of hospital pharmacy : science and practice · 2021Pooled it
- Prevalence of potential drug-drug interactions and associated factors among outpatients and inpatients in Ethiopian hospitals: a systematic review and meta-analysis of observational studies.BMC pharmacology & toxicology · 2020Pooled it
- Drug-drug interactions and their harmful effects in hospitalised patients: a systematic review and meta-analysis.European journal of clinical pharmacology · 2018Pooled it
- Information Technology-Based Interventions to Improve Drug-Drug Interaction Outcomes: A Systematic Review on Features and Effects.Journal of medical systems · 2017Pooled it
- Prevalence of statin-drug interactions in older people: a systematic review.European journal of clinical pharmacology · 2016Pooled it
- Drug-drug interactions in inpatient and outpatient settings in Iran: a systematic review of the literature.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2014Pooled it
- Educational effects of a workshop on quantitative drug-drug interaction assessment for pharmacists: a pre-post study.Journal of pharmaceutical health care and sciences · 2026Article
- Point-Prevalence of Antimicrobial-Related Potential Drug-Drug Interactions in Hospitalized Older Adults: A Multicenter Study Using Lexicomp.Journal of clinical medicine · 2026Article
- An LC-MS/MS Method for Simultaneous Determination of Almonertinib and Atorvastatin: Evaluating Their Drug-Drug Interactions in Rat.Drug design, development and therapy · 2026Article
- A retrospective study on potential drug‒drug interactions in patients with severe asthma receiving biological therapy: a single-center experience.BMC pulmonary medicine · 2025Observational
- Article
- Pharmacokinetics and pharmacodynamics of drug‒drug interactions in hospitalized older adults treated with direct oral anticoagulants.Aging clinical and experimental research · 2024Article
- TLC-Act: A Novel Tool for Managing Drug Interactions.The Canadian journal of hospital pharmacy · 2022Article
- Ambulatory Heart Function and Transplant Patients' Perceptions of Drug-Drug Interactions: A Qualitative Study.The Canadian journal of hospital pharmacy · 2022Article
- Drug interactions in the treatment of rheumatoid arthritis and psoriatic arthritis.Rheumatology international · 2020Review
- Risk Factors Associated With Medication Errors Among Patients Suffering From Chronic Disorders.Frontiers in public health · 2020Article
- Potential drug-drug interactions in deceased inpatients.Internal and emergency medicine · 2019Observational
- Prescribing error at hospital discharge: a retrospective review of medication information in an Irish hospital.Irish journal of medical science · 2017Article
- Potential drug related problems detected by electronic expert support system in patients with multi-dose drug dispensing.International journal of clinical pharmacy · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aim of the reviewTo study the prevalence of drug interactions in hospital healthcare by reviewing literature.
methodA review was carried out of studies written in Spanish and English on the prevalence of drug interactions in hospital care published in Pubmed between January 1990 and September 2008. The search strategy combined free text and MeSH terms, using the following keywords: "Drug interaction", "prevalence" and "hospital". For each article, we classified independent variables (pathology, age of population, whether patients were hospitalized or not, geographical location, etc.) and dependent variables (number of interactions per 100 patients studied, prevalence of patients with interactions, most common drug interactions, and others).
resultsThe search generated 436 articles. Finally, 47 articles were selected for the study, 3 provided results about drug interactions with real clinical consequences, 42 about potential interactions, and 2 described both. The prevalence of patients with interactions was between 15 and 45 % and the number of interactions per 100 patients was between 37 and 106, depending on the group of studies analyzed. There was a considerable increase in these rates in patients with heart diseases and elderly persons.
conclusionThere is a large number of studies on the prevalence of drug interactions in hospitals but they report widely varying results. The prevalence is higher in patients with heart diseases and elderly people.
Indexed as
Identifiers
22965222What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.